GenomeNet

Database: UniProt
Entry: DNAA_GEODF
LinkDB: DNAA_GEODF
Original site: DNAA_GEODF 
ID   DNAA_GEODF              Reviewed;         445 AA.
AC   B9M7S1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   28-MAR-2018, entry version 54.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Geob_0001;
OS   Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=316067;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22248 / JCM 15807 / FRC-32;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Kostka J., Richardson P.;
RT   "Complete sequence of Geobacter sp. FRC-32.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP001390; ACM18379.1; -; Genomic_DNA.
DR   RefSeq; WP_012645108.1; NC_011979.1.
DR   SMR; B9M7S1; -.
DR   STRING; 316067.Geob_0001; -.
DR   EnsemblBacteria; ACM18379; ACM18379; Geob_0001.
DR   KEGG; geo:Geob_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   BioCyc; GDAL316067:G1GUR-1-MONOMER; -.
DR   Proteomes; UP000007721; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    445       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000189798.
FT   NP_BIND     150    157       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   445 AA;  51122 MW;  8A5CCF232A89D11F CRC64;
     MEKIWLEAQS NIKKVLTPQT YNTWIKPIHF HNVSDTNLTL EVPSKFIKEW VTEKYLSIII
     EAISSLTNIK YQVDFKITEK SQVEKKKVDL QATEKIENDS TRNVDFNTNL NPKYTFDSFV
     CGASNQFAHA ASQAVANNPA CNYNPLFIYG GVGLGKTHLL IAIGNQIREN NKKAKICYYS
     SEKFMNEMIN SLRYKKMDEF RNKFRKMDIL LIDDIQFMAG KEATQEEFFH TFNALYESHK
     QIVVTSDKFP KDIPGLEERL RSRFEWGLIA DIQPPDIETK IAILKKKSDL NSITLPNDVA
     LFLASSATSN VRELEGMLIR LGAYASLTGS EISLNMARDI LKDIIVEKTK DITVEMIQKH
     VADHFKIKVS ELKSDKRLKT FVIPRQIAIY ISRELTKASY PEIGERFGGK DHSTIIHSVK
     KIEKQMENDL EIKNTVEKMK KELMS
//
DBGET integrated database retrieval system