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Database: UniProt
Entry: DNAA_GEOMG
LinkDB: DNAA_GEOMG
Original site: DNAA_GEOMG 
ID   DNAA_GEOMG              Reviewed;         450 AA.
AC   Q39ZS3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   07-JUN-2017, entry version 78.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Gmet_0001;
OS   Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=269799;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS-15 / ATCC 53774 / DSM 7210;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Geobacter metallireducens GS-15.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000148; ABB30251.1; -; Genomic_DNA.
DR   RefSeq; WP_004513720.1; NC_007517.1.
DR   ProteinModelPortal; Q39ZS3; -.
DR   SMR; Q39ZS3; -.
DR   STRING; 269799.Gmet_0001; -.
DR   EnsemblBacteria; ABB30251; ABB30251; Gmet_0001.
DR   KEGG; gme:Gmet_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000007073; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    450       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048649.
FT   NP_BIND     155    162       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   450 AA;  50943 MW;  2A910CF1ACB9A391 CRC64;
     MEDVWLQAQS NLAKVLTHQT FTTWIEPIRF AGAHKNTLLL EAPNQFIRDR VRESYLPMIL
     ESVRSLTDSH FQVELQVAAR QQEKTAKSPR KSHTEDELGP VESEKCAPAE FSTNLNAKYT
     FDTFVCGGSN QFAHAAALSV ANNPAGKYNP LFIYGGVGLG KTHLLTAIGN QVLTKNRKAR
     VCFYTSEKFM NELINCLRYQ KMEQFRNKFR KMDLLLIDDI QFIAGKERTQ EEFFHTFNAL
     YESHKQIVVT SDKFPKDIPG LEERLRSRFE WGLIADIQPP DTETKVAILS KKADSDGIRL
     PDDVALFLAS SASTNVRELE GMLIRLGAVA SLTGKNITLD MAREVLKDII VDKTKEVTVE
     MIQKYVADHF NIKVAELKSD KRLKALVVPR QIAIYLCRDL TKASYPDIGE KFGGKDHSTI
     IHSVKKVDKL LSQDFELKST IETLRKGLLN
//
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