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Database: UniProt
Entry: DNAA_GEOUR
LinkDB: DNAA_GEOUR
Original site: DNAA_GEOUR 
ID   DNAA_GEOUR              Reviewed;         449 AA.
AC   A5GDX1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   07-JUN-2017, entry version 67.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Gura_0001;
OS   Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=351605;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rf4;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Shelobolina E., Aklujkar M., Lovley D., Richardson P.;
RT   "Complete sequence of Geobacter uraniireducens Rf4.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000698; ABQ24219.1; -; Genomic_DNA.
DR   RefSeq; WP_011936948.1; NC_009483.1.
DR   ProteinModelPortal; A5GDX1; -.
DR   SMR; A5GDX1; -.
DR   STRING; 351605.Gura_0001; -.
DR   EnsemblBacteria; ABQ24219; ABQ24219; Gura_0001.
DR   KEGG; gur:Gura_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006695; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    449       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000079951.
FT   NP_BIND     154    161       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   449 AA;  51362 MW;  AE8C989D575903A3 CRC64;
     MEKVWLEAQS NIKKVLTPQT YNTWIKPIRF HTLTDDNLTL EVPSKFIKEW VTEKYLPMIV
     EAISSLTSVK YQIEFKITEK IPLESKPVDN FTPVIKDNEP SKETNKNIDI TANLNPKYTF
     DSFVCGASNQ FAHAASQAVA SNPASNYNPL FIYGGVGLGK THLLIAIGNH IKENNKKAKI
     CYYSSEKFMN EMINCLRYKK MDEFRNKFRK MDILLIDDIQ FMAGKEATQE EFFHTFNALY
     ESHKQIVVTS DKFPKDIPGL EERLRSRFEW GLIADIQPPD IETKIAILKK KSDLNSITLP
     NDVALFLASS ATSNVRELEG MLIRLGAYAS LTGSEITLNM ARDILKDIIV EKTKDITVEM
     IQKHVAEHFK IKVSELKSDK RLKTFVVPRQ IAIFICRELT KSSYPEIGEK FGGKDHSTII
     HSVKKIEKQM ANDLEIKNIV ENLKKELIT
//
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