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Database: UniProt
Entry: DNAA_HALHL
LinkDB: DNAA_HALHL
Original site: DNAA_HALHL 
ID   DNAA_HALHL              Reviewed;         449 AA.
AC   A1WWE0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   05-JUL-2017, entry version 70.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Hhal_1227;
OS   Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira
OS   halophila (strain DSM 244 / SL1)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Halorhodospira.
OX   NCBI_TaxID=349124;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 244 / SL1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Hoff W., Richardson P.;
RT   "Complete sequence of Halorhodospira halophila SL1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000544; ABM62002.1; -; Genomic_DNA.
DR   ProteinModelPortal; A1WWE0; -.
DR   SMR; A1WWE0; -.
DR   STRING; 349124.Hhal_1227; -.
DR   EnsemblBacteria; ABM62002; ABM62002; Hhal_1227.
DR   KEGG; hha:Hhal_1227; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   BioCyc; HHAL349124:GI3I-1264-MONOMER; -.
DR   Proteomes; UP000000647; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    449       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048653.
FT   NP_BIND     154    161       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   449 AA;  50744 MW;  EED661CA21FA7C7D CRC64;
     MDDSLWSACL QQLEREIPEQ QLNTWIRPLQ AHLEGDALRL YAPNRFVLDW VRDNFSARIG
     ELLAEIRPDE HLRVELEIGS PPTPDQREAA TGATRAAPAQ RSSEPRQRPV DSNLNPGFTF
     DSFVEGKSNQ LARAASMQVA DNPGGAYNPL FLYGGVGLGK THLMHAVGNA IRTARPEARV
     LYLHSERFVA EMVKALQHNA INEFKRHYRN LDALLIDDIQ FFAGKERSQE EFFHTFNALL
     ESEQQVIMTC DRYPKEVNGL EERLKSRFGW GLTVAIEPPE LETRVAILKS KAIRDGVDLP
     DEVAFFVAKR LRSNVRELEG ALRRITANAQ FTGRAIDVDF AKEALRDLLA LQDKLVTIDN
     IQKTVAAYYK IRVGDLLSKR RSRSITRPRH MAMVLAKELT SHSLPEIGDA FGGRDHSTVL
     HACRNIKSLI EDDARLAEDY DNLLRTLST
//
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