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Database: UniProt
Entry: DNAA_IDILO
LinkDB: DNAA_IDILO
Original site: DNAA_IDILO 
ID   DNAA_IDILO              Reviewed;         454 AA.
AC   Q5QY39;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-OCT-2017, entry version 82.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=IL0001;
OS   Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Idiomarinaceae; Idiomarina.
OX   NCBI_TaxID=283942;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-735 / DSM 15497 / L2-TR;
RX   PubMed=15596722; DOI=10.1073/pnas.0407638102;
RA   Hou S., Saw J.H., Lee K.S., Freitas T.A., Belisle C., Kawarabayasi Y.,
RA   Donachie S.P., Pikina A., Galperin M.Y., Koonin E.V., Makarova K.S.,
RA   Omelchenko M.V., Sorokin A., Wolf Y.I., Li Q.X., Keum Y.S.,
RA   Campbell S., Denery J., Aizawa S., Shibata S., Malahoff A., Alam M.;
RT   "Genome sequence of the deep-sea gamma-proteobacterium Idiomarina
RT   loihiensis reveals amino acid fermentation as a source of carbon and
RT   energy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:18036-18041(2004).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AE017340; AAV80845.1; -; Genomic_DNA.
DR   RefSeq; WP_011233265.1; NC_006512.1.
DR   ProteinModelPortal; Q5QY39; -.
DR   SMR; Q5QY39; -.
DR   STRING; 283942.IL0001; -.
DR   EnsemblBacteria; AAV80845; AAV80845; IL0001.
DR   KEGG; ilo:IL0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001171; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    454       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114190.
FT   NP_BIND     159    166       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   454 AA;  51511 MW;  C9E2FD0F1D19A423 CRC64;
     MNNSLWQQCA ERLQSELPLQ QFNTWIRPLQ AKLNGETLTL FAPNIYSVDW VRDKYLKTIN
     TYLEALCDDK VPNVVLKVGE ASPTQRDSGS PQRAAATRRK TPNFSSGNTD VEVPFESNIH
     PEYTFDNFVE GKSNQLARAA AIQVAENPGG VYNPLFVYGG TGLGKTHLLH AVGNGIMAHK
     KDAKVFYIRA ERFVQDMVNS IRNSSTNEFK RYYRSVDALL IDDIHFFANK KGSQEEFFHT
     FNALLEGNQQ IIMTSDLYPK EIDGVEDRLK SRFGWGLTIA IEPPELETRV AILMRKADER
     GLHMPHEVAF FIAKRLRSNV RELEGALNRV VANVQLTGRP ITIDFVREAL RDLIAAQEKL
     VTIDNIQKTV AEYYNIKLAD ILSKRRSRSV ARPRQLAMAL AKELTNHSLP EIGDAFGGRD
     HTTVLHACRK IQELKDAQHD IKEDYRNLIR TLSS
//
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