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Database: UniProt
Entry: DNAA_JANSC
LinkDB: DNAA_JANSC
Original site: DNAA_JANSC 
ID   DNAA_JANSC              Reviewed;         475 AA.
AC   Q28WI0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   30-AUG-2017, entry version 73.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Jann_0001;
OS   Jannaschia sp. (strain CCS1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Jannaschia.
OX   NCBI_TaxID=290400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCS1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E.,
RA   Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Moran M.A.,
RA   Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P.;
RT   "Complete sequence of chromosome of Jannaschia sp. CCS1.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000264; ABD52918.1; -; Genomic_DNA.
DR   RefSeq; WP_011453127.1; NC_007802.1.
DR   ProteinModelPortal; Q28WI0; -.
DR   STRING; 290400.Jann_0001; -.
DR   PRIDE; Q28WI0; -.
DR   EnsemblBacteria; ABD52918; ABD52918; Jann_0001.
DR   KEGG; jan:Jann_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235660; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000008326; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    475       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048658.
FT   NP_BIND     175    182       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   475 AA;  53129 MW;  E2DAC0C8FAA396E9 CRC64;
     MTNDTWNEVR QDLLKVVGKN NFSAWIEPID FDRIDERTAH FHVPTNFIGS WVTNNFGDLI
     LRQLSAHGAG ADRVKFTVSP KAGAAVAAPA NTSAPRPVPE MAAAAPAPAP VHHTAPAPAP
     VAAPAQPREL PGAKLNPNFT FANFVVGKPN ELAHAAARRV AETLDVTFNP LFLYGGVGLG
     KTHLMHAIAW DLQDRHPDAK ILFLSAEQFM HRFVRALREQ DTFNFKETFR SVDILMVDDV
     QFIAGKTSTQ QEFFHTFNAL VEMGKQIVIS GDRAPVDMEE LDNRIASRLQ CGLVVDIHPT
     DYELRLGVLQ HKAELLGAKY PHITFATGVL EYLAQKISSN VRVLEGALTR LFAFADLVRR
     EVTVDLAKEC LTDVLRATDK KVTMDEILKK TCEYYKIRQV DMISQNRQRV IARPRQMAMY
     LCKRLTTRSL PEIGKKFGGR DHTTILYGVR KIEELMQADS QIAEDAELLR RTLEA
//
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