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Database: UniProt
Entry: DNAA_LEIXX
LinkDB: DNAA_LEIXX
Original site: DNAA_LEIXX 
ID   DNAA_LEIXX              Reviewed;         473 AA.
AC   Q6AHN6;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   25-OCT-2017, entry version 83.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Lxx00010;
OS   Leifsonia xyli subsp. xyli (strain CTCB07).
OC   Bacteria; Actinobacteria; Micrococcales; Microbacteriaceae; Leifsonia.
OX   NCBI_TaxID=281090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CTCB07;
RX   PubMed=15305603; DOI=10.1094/MPMI.2004.17.8.827;
RA   Monteiro-Vitorello C.B., Camargo L.E.A., Van Sluys M.A.,
RA   Kitajima J.P., Truffi D., do Amaral A.M., Harakava R.,
RA   de Oliveira J.C.F., Wood D., de Oliveira M.C., Miyaki C.Y.,
RA   Takita M.A., da Silva A.C.R., Furlan L.R., Carraro D.M., Camarotte G.,
RA   Almeida N.F. Jr., Carrer H., Coutinho L.L., El-Dorry H.A.,
RA   Ferro M.I.T., Gagliardi P.R., Giglioti E., Goldman M.H.S.,
RA   Goldman G.H., Kimura E.T., Ferro E.S., Kuramae E.E., Lemos E.G.M.,
RA   Lemos M.V.F., Mauro S.M.Z., Machado M.A., Marino C.L., Menck C.F.,
RA   Nunes L.R., Oliveira R.C., Pereira G.G., Siqueira W., de Souza A.A.,
RA   Tsai S.M., Zanca A.S., Simpson A.J.G., Brumbley S.M., Setubal J.C.;
RT   "The genome sequence of the Gram-positive sugarcane pathogen Leifsonia
RT   xyli subsp. xyli.";
RL   Mol. Plant Microbe Interact. 17:827-836(2004).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AE016822; AAT88109.1; -; Genomic_DNA.
DR   RefSeq; WP_011185114.1; NC_006087.1.
DR   ProteinModelPortal; Q6AHN6; -.
DR   SMR; Q6AHN6; -.
DR   STRING; 281090.Lxx00010; -.
DR   EnsemblBacteria; AAT88109; AAT88109; Lxx00010.
DR   KEGG; lxx:Lxx00010; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001306; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    473       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114198.
FT   NP_BIND     174    181       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   473 AA;  53010 MW;  0CCE6EEB3D5F2CC0 CRC64;
     MADGEESISV AWQSVLDKLE TDDRITPQLH GFLSLVEPKG IMAGTFYLEV PNEFTRGMIE
     QRSRVPLLNA IGTLDNTLAV TTFAIVVNPE IQQESLSTVG EPEPTPAPYL DVATFTVAPP
     AEITAPPRNG DTRLNSKYSF DNFVIGQSNR FAHAAAVAVA EAPAKAYNPL FIYGDSGLGK
     THLLHAIGHY AMSLYPGIRV RYVSSEEFTN DFINSIANNR GSSFQARYRN IDILLIDDIQ
     FLQRAVETQE AFFHTFNTLH DHNKQVVITS DLPPKHLTGF EDRMRSRFEW GLITDVQVPD
     LETRIAILRK KAQSEKIQVP DDILEFMASK ISSNIRELEG TLIRVTAFAS LNRTPVDMPL
     VQTVLKDLIT LDDDNVIAPT DIITNTAEYF KLTVDDLYGS SRSQAVATAR QIAMYLCREL
     TNLSLPKIGQ LFGGRDHTTV MYANKKISEL MKERRSIYNQ VTELTSRIKQ NHR
//
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