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Database: UniProt
Entry: DNAA_MANSM
LinkDB: DNAA_MANSM
Original site: DNAA_MANSM 
ID   DNAA_MANSM              Reviewed;         457 AA.
AC   Q65VB8;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   25-OCT-2017, entry version 81.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=MS0485;
OS   Mannheimia succiniciproducens (strain MBEL55E).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Basfia.
OX   NCBI_TaxID=221988;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBEL55E;
RX   PubMed=15378067; DOI=10.1038/nbt1010;
RA   Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K.,
RA   Kim C.H., Jeong H., Hur C.G., Kim J.J.;
RT   "The genome sequence of the capnophilic rumen bacterium Mannheimia
RT   succiniciproducens.";
RL   Nat. Biotechnol. 22:1275-1281(2004).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AE016827; AAU37092.1; -; Genomic_DNA.
DR   RefSeq; WP_011199665.1; NC_006300.1.
DR   ProteinModelPortal; Q65VB8; -.
DR   SMR; Q65VB8; -.
DR   STRING; 221988.MS0485; -.
DR   EnsemblBacteria; AAU37092; AAU37092; MS0485.
DR   KEGG; msu:MS0485; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000607; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    457       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114204.
FT   NP_BIND     162    169       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   457 AA;  51806 MW;  02CE7F8D20B9491E CRC64;
     MERDLSQLWQ NCLLQLQDQI SSSDFGLWLR PLQADTSMPN TIVLYASNMF VKSWVENNYL
     AQITKIAQDL SNNTDLVIKV QEGSKPAARK VVAQQEIANT PVQHSAPMPE NEPQAAFRSN
     LNQHHLFENF VEGKSNQLAR AVGQKVANRP GDKSANPLFL YGGTGLGKTH LLHAVGNGII
     AGNSNARVVY IHAERFVQEY VKALKAERIE NFKKFYRSLD ALLIDDIQFF AGKDGTQEEF
     FNTFNSLFEG EKQIILTSDR YPREIEKIDD RLKSRFSWGL SIAIEPPDLE TRVAILMKKA
     EEKNIYLPEE VAFFIGQKLR TNVRELEGAL NRVHANADFT GKAITIDFVR ETLKDMLALQ
     DKLVTVENIQ KMVAEYYRIK VSDLKSKNRS RSIARPRQLA MALAKELTNR SLPEIGKAFG
     DRDHTTVLHA CRTIAALRDD DNNIQEDWSN LIRTLSA
//
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