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Database: UniProt
Entry: DNAA_NITEU
LinkDB: DNAA_NITEU
Original site: DNAA_NITEU 
ID   DNAA_NITEU              Reviewed;         459 AA.
AC   Q82Y84;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-OCT-2017, entry version 89.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=NE0001;
OS   Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 /
OS   NBRC 14298).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=228410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298;
RX   PubMed=12700255; DOI=10.1128/JB.185.9.2759-2773.2003;
RA   Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L.,
RA   Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A.,
RA   Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.;
RT   "Complete genome sequence of the ammonia-oxidizing bacterium and
RT   obligate chemolithoautotroph Nitrosomonas europaea.";
RL   J. Bacteriol. 185:2759-2773(2003).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AL954747; CAD83912.1; -; Genomic_DNA.
DR   RefSeq; WP_011110653.1; NC_004757.1.
DR   ProteinModelPortal; Q82Y84; -.
DR   SMR; Q82Y84; -.
DR   STRING; 228410.NE0001; -.
DR   EnsemblBacteria; CAD83912; CAD83912; NE0001.
DR   KEGG; neu:NE0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   PhylomeDB; Q82Y84; -.
DR   Proteomes; UP000001416; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    459       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114222.
FT   NP_BIND     164    171       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   459 AA;  52536 MW;  EE541D56B7A311A7 CRC64;
     MQKIETFWHF CLKHFRQELN GQQFNTWIKP LKLEVCPDEK NTLILIAPNR FVLQWIKDNF
     VTRIDEMAQD HFNERISFRL ELREPAESEA QTVRTSAQKN REDKKPAAEK TQGVTSRKTN
     PSQLNASFTF DAFVTGKANQ LARAGAIQVA ERPGIAYNPL FIYGGVGLGK THLMQAIGNY
     VLELDAGAKI RYVHAEKYVS DVVSAYQHKS FDKFKLYYHS LDLLLVDDVQ FFSGKNRTQE
     EFFYAFNALI EAHKQVIITS DCYPKEISGL EERLVSRFGW GLTVAIEPPE LEMRVAILLK
     KALAEKIELD ENTAFFIAKY IRSNVRELEG ALKRVLAFSR FTGHSISLDL AKEALKDLLA
     IQNRQISIEN IQKTVADYYK IKVADMYSKK RVRTIVRPRQ VAMAIAKELT QLSLPDIGEA
     FGGRDHTTVL HAHRKIIELR TSDPGINRDF NALMHILRG
//
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