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Database: UniProt
Entry: DNAA_NITMU
LinkDB: DNAA_NITMU
Original site: DNAA_NITMU 
ID   DNAA_NITMU              Reviewed;         476 AA.
AC   Q2YD61;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-OCT-2017, entry version 78.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Nmul_A0001;
OS   Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=323848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25196 / NCIMB 11849 / C 71;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT   25196.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000103; ABB73310.1; -; Genomic_DNA.
DR   RefSeq; WP_011379365.1; NC_007614.1.
DR   ProteinModelPortal; Q2YD61; -.
DR   SMR; Q2YD61; -.
DR   STRING; 323848.Nmul_A0001; -.
DR   EnsemblBacteria; ABB73310; ABB73310; Nmul_A0001.
DR   KEGG; nmu:Nmul_A0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002718; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    476       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048680.
FT   NP_BIND     181    188       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   476 AA;  53731 MW;  BAFAA7EA86BE4965 CRC64;
     MLAPDTFWLA CLEYFENELS AQQFNTWIKP LRLQLSDDSP EPALRLIAPN RFVLQWVKDN
     FLSDITQMAE NHFARPVQLQ LELAGQIPAS ASPSTGRNNG TASHSITAVF DAPTESAQKA
     PKDTKDTKDA KEKQEKNPTR LNPSFTFNTF VTGKANQLAR AGAIQVAERP GVAYNPFFIY
     GGVGLGKTHL IQAIGNFVVE QNPAAKVRYI HSEQYVSDVV RAYQHKAFDE FKRYYHSLDL
     LLIDDIQFFG GKNRTQEEFF YAFNALIEAH KQVIITCDSY PKEIAGMEER LISRFGWGLT
     VAVEPPELEM RVAILLKKAL MEDIILDESV AFFIAKHIRS NVRELEGALK RVVAYSRFTG
     HALTLDLARE ALKDLLAVQN RQISIENIQK TVADYYKIKV AEMYSKKRSR VVARPRQMAM
     AISKELTPLS LPDIGEAFGG RDHTTVLHGY RKIAELRASD PAVNRDFNTL LHILRG
//
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