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Database: UniProt
Entry: DNAA_NOSS1
LinkDB: DNAA_NOSS1
Original site: DNAA_NOSS1 
ID   DNAA_NOSS1              Reviewed;         459 AA.
AC   Q8YVG9;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-OCT-2017, entry version 89.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=alr2009;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T.,
RA   Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A.,
RA   Nakazaki N., Shimpo S., Sugimoto M., Takazawa M., Yamada M.,
RA   Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; BA000019; BAB73708.1; -; Genomic_DNA.
DR   PIR; AC2057; AC2057.
DR   ProteinModelPortal; Q8YVG9; -.
DR   SMR; Q8YVG9; -.
DR   STRING; 103690.alr2009; -.
DR   EnsemblBacteria; BAB73708; BAB73708; BAB73708.
DR   KEGG; ana:alr2009; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    459       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114121.
FT   NP_BIND     159    166       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   459 AA;  52350 MW;  0FB786414141F07A CRC64;
     MMEMPIDNLW SQVLERLQIE LSRPTFETWI KTANAERLEN NCLVIITPNP FARNWLQKYY
     ISTIANVVQS ILGHPVEIYI TVAKGEEFEE IGGGGEWELP TTNIINETPN QNRQPNTELN
     AKYVFSRFVV GANNRMAHAA SLAVAESPGR EFNPLFLCGG VGLGKTHLMQ AIGHYRWEIC
     PNSKIFYVST EQFTNDLITA IRNDSMQSFR EHYRAADVLL VDDIQFIEGK EYTQEEFFHT
     FNTLHEAGKQ VVIASDRPPN QIPSLQERLC SRFSMGLIAD IQAPDLETRM AILQKKSEYE
     KIRLPRDVIE YIATNFTSNI RELEGALTRA LAYISIWGLP MTVANLAPVL VTPMEKIEAT
     PEAILTVIAD NFDISIEDLK SNSRRREISW ARQIGMYLMR QHTDLSFPRI GEEFGGKDHT
     TVLYSCDKIA QLVESDRGLS QTLRQLSDRI KMNSRSRKP
//
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