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Database: UniProt
Entry: DNAA_OCEIH
LinkDB: DNAA_OCEIH
Original site: DNAA_OCEIH 
ID   DNAA_OCEIH              Reviewed;         447 AA.
AC   Q8EU88;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   07-JUN-2017, entry version 94.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=OB0001;
OS   Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 /
OS   KCTC 3954 / HTE831).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae;
OC   Oceanobacillus.
OX   NCBI_TaxID=221109;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831;
RX   PubMed=12235376; DOI=10.1093/nar/gkf526;
RA   Takami H., Takaki Y., Uchiyama I.;
RT   "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya
RT   Ridge and its unexpected adaptive capabilities to extreme
RT   environments.";
RL   Nucleic Acids Res. 30:3927-3935(2002).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; BA000028; BAC11957.1; -; Genomic_DNA.
DR   RefSeq; WP_011064403.1; NC_004193.1.
DR   ProteinModelPortal; Q8EU88; -.
DR   SMR; Q8EU88; -.
DR   STRING; 221109.OB0001; -.
DR   EnsemblBacteria; BAC11957; BAC11957; BAC11957.
DR   KEGG; oih:OB0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000822; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    447       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114224.
FT   NP_BIND     150    157       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   447 AA;  50693 MW;  D779DDF053CE2A85 CRC64;
     MENIEELWSA TLKKIEEKLS KPSFDTWLKN TKAEALEKDT LIISAPNEFA RDWLENQYTN
     LISQMLLEVT GSELNTKFII PDSLEEIEEQ KPMPKPKQST DTGDSPKSML NSKYTFDTFV
     IGAGNRFAHA ASLAVAEAPA KAYNPLFIYG GVGLGKTHLM HAIGHYVRDH NPNAKVVYLT
     SEKFTNEFIN AIMDNKSNHF RNKYRNIDVL LIDDIQFIAG KESTQEEFFH TFNALHGESK
     QIIISSDRPP KEIPTLEDRL RSRFEWGLIT DITPPDLETR IAILNKKAKA EGLDIPNEVM
     LYIANQINTN IRELEGALIR VVAYSSLVNQ DIDASLAADA LKDIIPSSKP KEITIPAIQE
     IVAERYHIRL EDFAAKKRTK SIAFPRQIAM YLSRELTDAS LPKIGEEFGG RDHTTVIHAH
     EKISKMLEQD TELDRDIEEL KEKLKSI
//
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