GenomeNet

Database: UniProt
Entry: DNAA_PROMA
LinkDB: DNAA_PROMA
Original site: DNAA_PROMA 
ID   DNAA_PROMA              Reviewed;         461 AA.
AC   Q51896;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   26-SEP-2003, sequence version 2.
DT   07-JUN-2017, entry version 109.
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
GN   Name=dnaA; OrderedLocusNames=Pro_0567;
OS   Prochlorococcus marinus (strain SARG / CCMP1375 / SS120).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochloraceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167539;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SARG / CCMP1375 / SS120;
RX   PubMed=9563839; DOI=10.1007/s004380050679;
RA   Richter S., Hess W.R., Krause M., Messer W.;
RT   "Unique organization of the dnaA region from Prochlorococcus marinus
RT   CCMP1375, a marine cyanobacterium.";
RL   Mol. Gen. Genet. 257:534-541(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SARG / CCMP1375 / SS120;
RX   PubMed=12917486; DOI=10.1073/pnas.1733211100;
RA   Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M.,
RA   Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F.,
RA   Makarova K.S., Ostrowski M., Oztas S., Robert C., Rogozin I.B.,
RA   Scanlan D.J., Tandeau de Marsac N., Weissenbach J., Wincker P.,
RA   Wolf Y.I., Hess W.R.;
RT   "Genome sequence of the cyanobacterium Prochlorococcus marinus SS120,
RT   a nearly minimal oxyphototrophic genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000305}.
DR   EMBL; U44977; AAC15822.1; -; Genomic_DNA.
DR   EMBL; AE017126; AAP99612.1; -; Genomic_DNA.
DR   PIR; T52496; T52496.
DR   RefSeq; NP_874960.1; NC_005042.1.
DR   RefSeq; WP_011124720.1; NC_005042.1.
DR   ProteinModelPortal; Q51896; -.
DR   SMR; Q51896; -.
DR   STRING; 167539.Pro0567; -.
DR   EnsemblBacteria; AAP99612; AAP99612; Pro_0567.
DR   GeneID; 1461949; -.
DR   KEGG; pma:Pro_0567; -.
DR   PATRIC; fig|167539.5.peg.582; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001420; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    461       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114233.
FT   NP_BIND     162    169       ATP. {ECO:0000255}.
FT   CONFLICT    302    302       Q -> H (in Ref. 1; AAC15822).
FT                                {ECO:0000305}.
SQ   SEQUENCE   461 AA;  51403 MW;  EFDD706038D721A3 CRC64;
     MLEASWEKVQ SSLKQNLSKP SYETWIRPTE FSGFKNGELT LIAPNSFSSA WLKNNYSQTI
     QETAEEIFGE PVTVHVKVKA NAESSDEHYS SAPITPPLEA SPGSVDSSGS SLRLSKKTLP
     LLNLRYVFNR FVVGPNSRMA HAAAMAVAES PGREFNPLFI CGGVGLGKTH LMQAIGHYRL
     EIDPGAKVSY VSTETFTNDL ILAIRQDRMQ AFRDRYRAAD LILVDDIQFI EGKEYTQEEF
     FHTFNALHDA GSQIVLASDR PPSQIPRLQE RLMSRFSMGL IADVQAPDLE TRMAILQKKA
     EQERVGLPRD LIQFIAGRFT SNIRELEGAL TRAIAFASIT GLPMTVDSIA PMLDPNGQGV
     EVTPKQVLDK VAEVFKVTPD EMRSASRRRP VSQARQVGMY LMRQGTNLSL PRIGDTFGGK
     DHTTVMYAIE QVEKKLSSDP QIASQVQKIR DLLQIDSRRK R
//
DBGET integrated database retrieval system