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Database: UniProt
Entry: DNAA_PROMP
LinkDB: DNAA_PROMP
Original site: DNAA_PROMP 
ID   DNAA_PROMP              Reviewed;         463 AA.
AC   P0A3A2; Q9S487;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-OCT-2017, entry version 84.
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
GN   Name=dnaA; OrderedLocusNames=PMM0565;
OS   Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 /
OS   MED4).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochloraceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=59919;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1986 / NIES-2087 / MED4;
RX   PubMed=12917642; DOI=10.1038/nature01947;
RA   Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P.,
RA   Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R.,
RA   Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M.,
RA   Shaw S.L., Steglich C., Sullivan M.B., Ting C.S., Tolonen A.,
RA   Webb E.A., Zinser E.R., Chisholm S.W.;
RT   "Genome divergence in two Prochlorococcus ecotypes reflects oceanic
RT   niche differentiation.";
RL   Nature 424:1042-1047(2003).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000305}.
DR   EMBL; BX548174; CAE19024.1; -; Genomic_DNA.
DR   RefSeq; WP_011132199.1; NC_005072.1.
DR   ProteinModelPortal; P0A3A2; -.
DR   SMR; P0A3A2; -.
DR   STRING; 59919.PMM0565; -.
DR   EnsemblBacteria; CAE19024; CAE19024; PMM0565.
DR   KEGG; pmm:PMM0565; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001026; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    463       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114236.
FT   NP_BIND     164    171       ATP. {ECO:0000255}.
SQ   SEQUENCE   463 AA;  51989 MW;  51F4138B1E659584 CRC64;
     MQAANPIWAE VQQLLQKNLS KPSFETWIRP AKFNCFENGL LTLITPNNFT SDWLRKNYSE
     TIEKAAEEIC GHNVKVVFKS ETNINNNSNS SDSVSQQNIN SQSKSFSINQ SNNLINRSKK
     SHSLNTRYVF KRFVVGPNSR MAHAAALAVA ESPGREFNPL FICGGVGLGK THLMQAVGHY
     RVEIDPDAKV LYVSTETFSS DLIQSIRKDG MHAFKNKYRS VDLLLIDDIQ FLEGKEYTQE
     EFFNTFNALY EAGKQIVIAS DRPPSQIPKL QERLISRFSM GLIADIQPPD IETRMAILQK
     KAEQERMNLP RDLIQFIAGR FSSNIRELEG AFTRAVAFAS ITGLPMTVQS IAPMLDPNSV
     GVVVTPKQVI KKVSDFFEVS AEELVSSSRR KPVSQARQIG MYLMRQGTDL SLPKIGDEFG
     GKDHTTVMYA IEQVEKKLSS DPNVASQVQK IKDLLQIDSR KNL
//
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