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Database: UniProt
Entry: DNAA_RHOJR
LinkDB: DNAA_RHOJR
Original site: DNAA_RHOJR 
ID   DNAA_RHOJR              Reviewed;         528 AA.
AC   Q0SAG7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   07-JUN-2017, entry version 73.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=RHA1_ro03666;
OS   Rhodococcus jostii (strain RHA1).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=101510;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RHA1;
RX   PubMed=17030794; DOI=10.1073/pnas.0607048103;
RA   McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M.,
RA   Fernandes C., Miyazawa D., Wong W., Lillquist A.L., Wang D.,
RA   Dosanjh M., Hara H., Petrescu A., Morin R.D., Yang G., Stott J.M.,
RA   Schein J.E., Shin H., Smailus D., Siddiqui A.S., Marra M.A.,
RA   Jones S.J.M., Holt R., Brinkman F.S.L., Miyauchi K., Fukuda M.,
RA   Davies J.E., Mohn W.W., Eltis L.D.;
RT   "The complete genome of Rhodococcus sp. RHA1 provides insights into a
RT   catabolic powerhouse.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000431; ABG95469.1; -; Genomic_DNA.
DR   RefSeq; WP_011596259.1; NC_008268.1.
DR   ProteinModelPortal; Q0SAG7; -.
DR   SMR; Q0SAG7; -.
DR   STRING; 101510.RHA1_ro03666; -.
DR   PRIDE; Q0SAG7; -.
DR   EnsemblBacteria; ABG95469; ABG95469; RHA1_ro03666.
DR   GeneID; 4221217; -.
DR   KEGG; rha:RHA1_ro03666; -.
DR   PATRIC; fig|101510.16.peg.3692; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000008710; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    528       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048708.
FT   NP_BIND     229    236       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   528 AA;  59215 MW;  7948DA27530BA0FE CRC64;
     MNDDPNALAR IWIDVVADLT SDSPGGDLPP LTRGQKAWLA LVKPLTLAQG FALLSVPSPF
     AQEAIERDLR EPILHALGRH LGEQVEGLGV RIAAPVDDEP ESDPPSRDHR PEPEPLHTPR
     HLEPSVTSSG SFRRRRFGSG EDQPYSDTTD FEEVDDDREA LASVHESWPS YFTKPPSGPA
     PSATGGNSLN AKYTFDTFVI GSSNRFAHAA AVAIAEAPAR AYNPLFVWGA SGLGKTHLLH
     AAGHYAQRLF PGMRVKYVST EEFTNDFINS LRDDRKVAFK RRYRETDVLL VDDIQFIEGK
     EGIQEEFFHT FNTLHNANKQ IVVSSDRPPK QLATLEERLR TRFEWGLITD VQPPELETRI
     AILSKKARMD RLEVPDDVLE LIASRIERNI RELEGALIRV TAFASLNRQP LDLTLAEVVL
     RDLMPDSSSL EINAATIMAV TAEYFNMSID DLCGPGKARP LASARQISMY LCRELTDLSL
     PKIGQTFGRD HTTVMYADKK IRKEMTERRK VYDQVQELTA RIKQRSKR
//
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