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Database: UniProt
Entry: DNAA_ROSDO
LinkDB: DNAA_ROSDO
Original site: DNAA_ROSDO 
ID   DNAA_ROSDO              Reviewed;         454 AA.
AC   Q16DK6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   07-JUN-2017, entry version 73.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=RD1_0208;
OS   Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter
OS   sp. (strain OCh 114)) (Roseobacter denitrificans).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Roseobacter.
OX   NCBI_TaxID=375451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33942 / OCh 114;
RX   PubMed=17098896; DOI=10.1128/JB.01390-06;
RA   Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J.,
RA   Ramos H., Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C.,
RA   Shah M.K., O'Huallachain M.E., Lince M.T., Blankenship R.E.,
RA   Beatty J.T., Touchman J.W.;
RT   "The complete genome sequence of Roseobacter denitrificans reveals a
RT   mixotrophic rather than photosynthetic metabolism.";
RL   J. Bacteriol. 189:683-690(2007).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000362; ABG29937.1; -; Genomic_DNA.
DR   RefSeq; WP_011566559.1; NZ_FOOO01000015.1.
DR   ProteinModelPortal; Q16DK6; -.
DR   SMR; Q16DK6; -.
DR   STRING; 375451.RD1_0208; -.
DR   EnsemblBacteria; ABG29937; ABG29937; RD1_0208.
DR   KEGG; rde:RD1_0208; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235660; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000007029; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    454       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048713.
FT   NP_BIND     154    161       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   454 AA;  51671 MW;  9E597FB709833B99 CRC64;
     MTKEQWGQLQ QRLLKTVGQN NYKNWIEPIE FGSTQDGVAT FEVPTNFLGN YVSQNFADLI
     LHEVRQEDPA VRRLRFAVPS HVNATTKPAR PAQATAPRAP AEKTPRSTLS TAPLDARFTF
     DNFIVGKPNE LAHAAAKRVA EGGPVTFNPL FLYGGVGLGK THLMHAIAHE LRLRRPEMNV
     LYLSAEQFMY RFVQALRDRK MMDFKEIFRS VDVLMVDDVQ FIAGKGSTQE EFFHTFNALV
     DQNKQIIISG DRAPGEIKDM EERVKSRLQC GLVVDLHPTD YELRLGILQS KVEQQRKNYP
     GLDISDGVLE FLAHRISTNV RVLEGALTRL CAFASLVGRE IDMELTQDCL SDVLRASERK
     ITVEEIQRKV SDHYNIRLSD MIGPKRLRSY ARPRQVAMYL SKKMTSRSLP EIGRRFGGRD
     HTTVMHGVKR IEELKIQDGQ IAEDLELLRR ALEE
//
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