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Database: UniProt
Entry: DNAA_RUEST
LinkDB: DNAA_RUEST
Original site: DNAA_RUEST 
ID   DNAA_RUEST              Reviewed;         470 AA.
AC   Q1GKT2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   27-JUN-2006, sequence version 1.
DT   07-JUN-2017, entry version 75.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=TM1040_0001;
OS   Ruegeria sp. (strain TM1040) (Silicibacter sp.).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=292414;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM1040;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Goodwin L.,
RA   Thompson L.S., Gilna P., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Belas R., Moran M.A., Buchan A., Gonzalez J.M.,
RA   Schell M.A., Sun F., Richardson P.;
RT   "Complete sequence of chromosome of Silicibacter sp. TM1040.";
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000377; ABF62734.1; -; Genomic_DNA.
DR   RefSeq; WP_011537372.1; NC_008044.1.
DR   ProteinModelPortal; Q1GKT2; -.
DR   SMR; Q1GKT2; -.
DR   STRING; 292414.TM1040_0001; -.
DR   EnsemblBacteria; ABF62734; ABF62734; TM1040_0001.
DR   KEGG; sit:TM1040_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235660; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000636; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    470       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048729.
FT   NP_BIND     170    177       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   470 AA;  53246 MW;  4ECECB5D93127424 CRC64;
     MTDDTWGLLR KRLLKTVGQN NFTTWIEPLE LDQVDGGVAT FHVPTNFMGN YVSQNFADLI
     LHEFNKSGEA VQRLAFKVAA NSPTRPVQPT MSEAIEEPAP LQTTVVDQLG NQEGNTSVKS
     PPEDLQAAPL DPRFTFDSFV VGKPNELAHA AARRVAEGGP VTFNPLVLYG GVGLGKTHLM
     HAIAWELKER NPELNVLYLS AEQFMYRFVQ ALRERKMMDF KHLFRSVDVL MVDDVQFIAG
     KDSTQEEFFH TFNALVDQNK QIIISADRAP GEIKDLEDRV KSRLQCGLVV DLHPTDYELR
     LGILQTKVQQ NRKNYPDLKI ADGVLELLAH RISTNVRVLE GALTRLFAFA SLVGREIDMD
     LTQDCLADVL RASERKITVE EIQRKVSEYY NIRMSDIIGP KRLRSYARPR QVAMYLCKQL
     TSRSLPEIGR RFGGRDHTTV MHGVRRIEEL KTIDGQIAED VEMLRRSLEA
//
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