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Database: UniProt
Entry: DNAA_SHEON
LinkDB: DNAA_SHEON
Original site: DNAA_SHEON 
ID   DNAA_SHEON              Reviewed;         460 AA.
AC   Q8EKT2;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-OCT-2017, entry version 99.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=SO_0008;
OS   Shewanella oneidensis (strain MR-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=211586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MR-1;
RX   PubMed=12368813; DOI=10.1038/nbt749;
RA   Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA   Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A.,
RA   Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J.,
RA   Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S.,
RA   Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A.,
RA   White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M.,
RA   Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J.,
RA   Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O.,
RA   Venter J.C., Nealson K.H., Fraser C.M.;
RT   "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT   Shewanella oneidensis.";
RL   Nat. Biotechnol. 20:1118-1123(2002).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AE014299; AAN53095.1; -; Genomic_DNA.
DR   RefSeq; NP_715650.1; NC_004347.2.
DR   RefSeq; WP_011070424.1; NC_004347.2.
DR   ProteinModelPortal; Q8EKT2; -.
DR   SMR; Q8EKT2; -.
DR   STRING; 211586.SO_0008; -.
DR   PaxDb; Q8EKT2; -.
DR   EnsemblBacteria; AAN53095; AAN53095; SO_0008.
DR   GeneID; 1167906; -.
DR   KEGG; son:SO_0008; -.
DR   PATRIC; fig|211586.12.peg.8; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   PhylomeDB; Q8EKT2; -.
DR   Proteomes; UP000008186; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; ISS:TIGR.
DR   GO; GO:0006260; P:DNA replication; ISS:TIGR.
DR   GO; GO:0006270; P:DNA replication initiation; IBA:GO_Central.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    460       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114254.
FT   NP_BIND     165    172       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   460 AA;  51970 MW;  C1523392D161D1DA CRC64;
     MAVSLWQQCI GRLQDELSAQ QFSMWIRPLQ AEMDGDTLVL YAPNRFVLDW VRDKYINIIN
     QFFTEQMGND APKLRFDIGS RPSAKKPEPA PVAAVRVPSP QTKASVGTAF NTTEPVANTN
     HRSNINPTYQ FDNFVEGKSN QLGKAAALQV AENPGGAYNP LFLYGGTGLG KTHLLHAVGN
     GIIKNNPNAK VVYMHSERFV QDMVKALQNN AIEEFKRYYR SVDALFIDDI QFFANKDRSQ
     EEFFHTFNAL LEGNHQIILT SDRYPKEIDG VEDRLKSRFG WGLTVAIEPP ELETRVAILM
     RKAQESGINL PDEVAFFIAK RLRSNVRELE GALNRVIANA NFTGRPITID FVREALRDLL
     ALQEKLVTID NIQKTVAEYY KIKMADMLSK RRSRSVARPR QVAMALSKEL TNQSLPEIGD
     AFGGRDHTTV LHACRKIAQL REESHDIKED YANLIRTLSS
//
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