GenomeNet

Database: UniProt
Entry: DNAA_STACT
LinkDB: DNAA_STACT
Original site: DNAA_STACT 
ID   DNAA_STACT              Reviewed;         453 AA.
AC   B9DPX4;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   07-JUN-2017, entry version 57.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Sca_2474;
OS   Staphylococcus carnosus (strain TM300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=396513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM300;
RX   PubMed=19060169; DOI=10.1128/AEM.01982-08;
RA   Rosenstein R., Nerz C., Biswas L., Resch A., Raddatz G.,
RA   Schuster S.C., Goetz F.;
RT   "Genome analysis of the meat starter culture bacterium Staphylococcus
RT   carnosus TM300.";
RL   Appl. Environ. Microbiol. 75:811-822(2009).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; AM295250; CAL29377.1; -; Genomic_DNA.
DR   RefSeq; WP_015901712.1; NC_012121.1.
DR   ProteinModelPortal; B9DPX4; -.
DR   SMR; B9DPX4; -.
DR   STRING; 396513.Sca_2474; -.
DR   KEGG; sca:SCA_2474; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   Proteomes; UP000000444; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    453       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000189808.
FT   NP_BIND     156    163       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   453 AA;  52188 MW;  0F8CB6C3C03DB558 CRC64;
     MSKEEIWDKV LELAKNELTP ISYSTWFEPP KTELIDIQEN TAIILVESNF VQDFLKKQYT
     DIIADLIEKA IGTKLMPNFV IQEDLTEDKQ VKDSAKAKSE AKPDVQAPQN SSEDQFNVHN
     TFETFVIGPG NRFPHAASLA VAEAPAKAYN PLFIYGGVGL GKTHLMHAIG HYVLENNRDA
     KVIYTSSEKF TNEFIKSIRD NETEQFREKY RNIDVLLIDD IQFIQNKEQT QEEFFHTFND
     LHQTGKQIVI SSDRPPKEIA KLEDRLRSRF EWGLIVDITP PDYETRMAIL QKKLEEEDVD
     IPLESLTYIA NQIQSNIREL EGALTRVIAY SRLQNEAITT ELTAEALKDI IQTPKSKKIT
     IQDIQKVVGQ YYNVRLEDFA AKKRTKSIAY PRQIAMYLSR ELTDFSLPKI GEEFGGRDHT
     TVIHAHMKIQ TDMSEDPIFK QEVENLEKEI RNQ
//
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