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Database: UniProt
Entry: DNAA_SYNJB
LinkDB: DNAA_SYNJB
Original site: DNAA_SYNJB 
ID   DNAA_SYNJB              Reviewed;         467 AA.
AC   Q2JHS1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   07-JUN-2017, entry version 74.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=CYB_0001;
OS   Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium
OS   Yellowstone B-Prime).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=321332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JA-2-3B'a(2-13);
RX   PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA   Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M.,
RA   Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT   "Population level functional diversity in a microbial community
RT   revealed by comparative genomic and metagenomic analyses.";
RL   ISME J. 1:703-713(2007).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000240; ABD01003.1; -; Genomic_DNA.
DR   RefSeq; WP_011431674.1; NC_007776.1.
DR   ProteinModelPortal; Q2JHS1; -.
DR   SMR; Q2JHS1; -.
DR   STRING; 321332.CYB_0001; -.
DR   EnsemblBacteria; ABD01003; ABD01003; CYB_0001.
DR   KEGG; cyb:CYB_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000001938; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    467       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000048748.
FT   NP_BIND     167    174       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   467 AA;  52328 MW;  F0C974723C2D3704 CRC64;
     MDISLDQLWD EALCHLQVQL SRPTFEAWIK TARAESLVDN RLTICTPSEW ARGWLQKHYA
     STITEVVQRV AGIPLQVEFS VSPHASVEAE PPSRAISPTS GRAGSLPAST TLGLEVGGSL
     PMRAPDLNPK YSFSRFVVGP NNRMAHAAAL AVADKPGRAY NPLFLCGGVG LGKTHLMQAI
     GHYQLEANPQ AKVFYVSTER FTNDLIDAIR RDSMQSFREH YRDVDILLVD DVQFIEGKEY
     TQEEFFHTFN TLHESGKQIV LAADRSPHLI PRLQERLCSR FSMGLIAEIQ SPDIETRMAI
     LKKKAEYEGM NLPADVIEYI ATTYTSNIRE LEGALIRAVA YVSISGLPMS VETIQPILNP
     PSEPKEITAD MITDVVCEEF GIDRDSLLGS SRKRDISQAR QIAMFLMRHY TNLSLPKIGD
     YFGGKDHTTV LYSCEKVSQL QRQSLQFERQ LQKLVERLRV VANSRSS
//
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