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Database: UniProt
Entry: DNAA_THEEB
LinkDB: DNAA_THEEB
Original site: DNAA_THEEB 
ID   DNAA_THEEB              Reviewed;         453 AA.
AC   Q8DL93;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-OCT-2017, entry version 89.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=tlr0603;
OS   Thermosynechococcus elongatus (strain BP-1).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y.,
RA   Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Nakazaki N.,
RA   Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; BA000039; BAC08155.1; -; Genomic_DNA.
DR   RefSeq; NP_681393.1; NC_004113.1.
DR   RefSeq; WP_011056451.1; NC_004113.1.
DR   ProteinModelPortal; Q8DL93; -.
DR   SMR; Q8DL93; -.
DR   STRING; 197221.tlr0603; -.
DR   EnsemblBacteria; BAC08155; BAC08155; BAC08155.
DR   GeneID; 1011558; -.
DR   KEGG; tel:tlr0603; -.
DR   PATRIC; fig|197221.4.peg.637; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235658; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    453       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114283.
FT   NP_BIND     153    160       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   453 AA;  51054 MW;  E898C60241ED5B01 CRC64;
     MISSAEDLWH QILERLQLLL SRPTFETWIK TATVQSFDGQ TLTICTPNPF ARNWLQKYYL
     KTIADVAREI VGKPVEIELA IAQGAEHDTS IRPTSRGEVE ATPPAARHRG SELNPKYVFS
     RYVVGPNNRM AHAACLAVAE SPGREFNPLF LCGGVGLGKT HLMQAIGHYR LEIDPNAKIF
     YVSTEQFTND LIAAIRKDSM QSFREHYRAV DVMLVDDIQF IEGKEYTQEE FFHTFNTLHE
     AGKQVVLASD RPPSQIPRLQ ERLCSRFSMG LIADIQPPDL ETRMAILQKK AEYENIRLPR
     EVIEYIAASY TSNIRELEGA LIRAVAYISI SGLPMTVENI APVLSPTVRK IETSPEIILK
     VVSEALNVPI SDLKGNSRRR EISMARQVGM YLMRQYTGLS LPKIGEEFGG KDHTTVMYSC
     DKVAELQRTD PEMGSLLRQL SDRINLASRS TEP
//
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