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Database: UniProt
Entry: DNAA_XANP2
LinkDB: DNAA_XANP2
Original site: DNAA_XANP2 
ID   DNAA_XANP2              Reviewed;         506 AA.
AC   A7IB67;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   07-JUN-2017, entry version 64.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   OrderedLocusNames=Xaut_0001;
OS   Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Xanthobacter.
OX   NCBI_TaxID=78245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1158 / Py2;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.,
RA   Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Brainard J.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Ensigns S.A., Richardson P.;
RT   "Complete sequence of chromosome of Xanthobacter autotrophicus Py2.";
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
DR   EMBL; CP000781; ABS65260.1; -; Genomic_DNA.
DR   RefSeq; WP_011995680.1; NC_009720.1.
DR   ProteinModelPortal; A7IB67; -.
DR   SMR; A7IB67; -.
DR   STRING; 78245.Xaut_0001; -.
DR   EnsemblBacteria; ABS65260; ABS65260; Xaut_0001.
DR   KEGG; xau:Xaut_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235660; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002417; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    506       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_1000122035.
FT   NP_BIND     207    214       ATP. {ECO:0000255|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   506 AA;  55420 MW;  339ABB8CDAC8CB72 CRC64;
     MECATTATTP WERVRQRLRE EIGEEKFTSW FARMDLDKLT ADAVQLSVPT RFLKSWIQEN
     YLPRIADIWA EESGAKRRVD LAVRNAFARP VALKANTVRE VVTERTDMHS GDTRQQSARI
     SDGRSTDARG ADGRGSDARA VEPRAAAAAL SDAVAGDVAS GSPLDARLTF ETFVVGKSNS
     LAFAAAKQVA ESAPGSAPVF NPLYLHAAVG LGKTHLLQAI ARAGAVGGRR TTYLTAERFM
     YGFVAALKTH SAIAFKDALR TIDTLVIDDL QFLKGNNLQQ EFCHTLNALL DGGRQVVVAA
     DCLPGELEHL DERVRSRLAG GLVVELAALE EDLRLEILKA RYQTLTEQHP GFAVPAPVLE
     FLARSVGQSG RDLDGALNKL LAFNQLTGEP VTLEMAENAV KDLIRPTDPK RVRVDDILRV
     VAKHYNVSRA DLLSQRRTAT VVKPRQIAMY LAKTLTLRSL PEIGRRFGGR DHTTVLHAVR
     KIDGLVNADR ALAEEIEVLK RLALEA
//
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