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Database: UniProt
Entry: DNAA_XYLFA
LinkDB: DNAA_XYLFA
Original site: DNAA_XYLFA 
ID   DNAA_XYLFA              Reviewed;         439 AA.
AC   Q9PHE3;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-OCT-2017, entry version 100.
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
GN   Name=dnaA; OrderedLocusNames=XF_0001;
OS   Xylella fastidiosa (strain 9a5c).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xylella.
OX   NCBI_TaxID=160492;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9a5c;
RX   PubMed=10910347; DOI=10.1038/35018003;
RA   Simpson A.J.G., Reinach F.C., Arruda P., Abreu F.A., Acencio M.,
RA   Alvarenga R., Alves L.M.C., Araya J.E., Baia G.S., Baptista C.S.,
RA   Barros M.H., Bonaccorsi E.D., Bordin S., Bove J.M., Briones M.R.S.,
RA   Bueno M.R.P., Camargo A.A., Camargo L.E.A., Carraro D.M., Carrer H.,
RA   Colauto N.B., Colombo C., Costa F.F., Costa M.C.R., Costa-Neto C.M.,
RA   Coutinho L.L., Cristofani M., Dias-Neto E., Docena C., El-Dorry H.,
RA   Facincani A.P., Ferreira A.J.S., Ferreira V.C.A., Ferro J.A.,
RA   Fraga J.S., Franca S.C., Franco M.C., Frohme M., Furlan L.R.,
RA   Garnier M., Goldman G.H., Goldman M.H.S., Gomes S.L., Gruber A.,
RA   Ho P.L., Hoheisel J.D., Junqueira M.L., Kemper E.L., Kitajima J.P.,
RA   Krieger J.E., Kuramae E.E., Laigret F., Lambais M.R., Leite L.C.C.,
RA   Lemos E.G.M., Lemos M.V.F., Lopes S.A., Lopes C.R., Machado J.A.,
RA   Machado M.A., Madeira A.M.B.N., Madeira H.M.F., Marino C.L.,
RA   Marques M.V., Martins E.A.L., Martins E.M.F., Matsukuma A.Y.,
RA   Menck C.F.M., Miracca E.C., Miyaki C.Y., Monteiro-Vitorello C.B.,
RA   Moon D.H., Nagai M.A., Nascimento A.L.T.O., Netto L.E.S.,
RA   Nhani A. Jr., Nobrega F.G., Nunes L.R., Oliveira M.A.,
RA   de Oliveira M.C., de Oliveira R.C., Palmieri D.A., Paris A.,
RA   Peixoto B.R., Pereira G.A.G., Pereira H.A. Jr., Pesquero J.B.,
RA   Quaggio R.B., Roberto P.G., Rodrigues V., de Rosa A.J.M.,
RA   de Rosa V.E. Jr., de Sa R.G., Santelli R.V., Sawasaki H.E.,
RA   da Silva A.C.R., da Silva A.M., da Silva F.R., Silva W.A. Jr.,
RA   da Silveira J.F., Silvestri M.L.Z., Siqueira W.J., de Souza A.A.,
RA   de Souza A.P., Terenzi M.F., Truffi D., Tsai S.M., Tsuhako M.H.,
RA   Vallada H., Van Sluys M.A., Verjovski-Almeida S., Vettore A.L.,
RA   Zago M.A., Zatz M., Meidanis J., Setubal J.C.;
RT   "The genome sequence of the plant pathogen Xylella fastidiosa.";
RL   Nature 406:151-159(2000).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000305}.
DR   EMBL; AE003849; AAF82814.1; -; Genomic_DNA.
DR   PIR; G82859; G82859.
DR   RefSeq; WP_010892550.1; NC_002488.3.
DR   ProteinModelPortal; Q9PHE3; -.
DR   SMR; Q9PHE3; -.
DR   STRING; 160492.XF0001; -.
DR   EnsemblBacteria; AAF82814; AAF82814; XF_0001.
DR   GeneID; 1125511; -.
DR   KEGG; xfa:XF_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; VENWVKD; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000812; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA replication;
KW   DNA-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1    439       Chromosomal replication initiator protein
FT                                DnaA.
FT                                /FTId=PRO_0000114308.
FT   NP_BIND     144    151       ATP. {ECO:0000255}.
SQ   SEQUENCE   439 AA;  50164 MW;  796E198F3F1085D5 CRC64;
     MESWSRCLER LETEFPPEDV HTWLRPLQAD QRGDSVVLYA PNPFIIELVE ERYLGRLREL
     LSYFSGIREV VLAIGSRPKT TELPVPVDTT GRLSSTVPFN GNLDTHYNFD NFVEGRSNQL
     ARAAAWQAAQ KPGDRTHNPL LLYGGTGLGK THLMFAAGNV MRQVNPTYKV MYLRSEQFFS
     AMIRALQDKS MDQFKRQFHQ IDALLIDDIQ FFAGKDRTQE EFFHTFNALF DGKQQIILTC
     DRYPREVNGL EPRLKSRLAW GLSVAIDPPD FETRAAIVLA KARERGATIP DEVAFLIAKK
     MHSNVRDLEG ALNTLVARAN FTGRAVTIEF SQETLRDLLR AQQQTIGIPN IQKIVADYYG
     LQIKDLLSKR RTRSLARPRQ LAMALAKELT EHSLPEIGDA FAGRDHTTVL HACRQIKLLM
     ETETKLREDW DKLMRKFSE
//
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