ID DRB4_ORYSJ Reviewed; 312 AA.
AC Q6YW64; A0A0P0XG44;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE RecName: Full=Double-stranded RNA-binding protein 4;
DE AltName: Full=dsRNA-binding protein 4;
GN Name=DRB4; OrderedLocusNames=Os08g0384100, LOC_Os08g29530;
GN ORFNames=B1090H08.31;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Binds double-stranded RNA. {ECO:0000250}.
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DR EMBL; AP005795; BAD05825.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF23614.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT05244.1; -; Genomic_DNA.
DR EMBL; AK065829; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015650897.1; XM_015795411.1.
DR AlphaFoldDB; Q6YW64; -.
DR SMR; Q6YW64; -.
DR STRING; 39947.Q6YW64; -.
DR PaxDb; 39947-Q6YW64; -.
DR EnsemblPlants; Os08t0384100-01; Os08t0384100-01; Os08g0384100.
DR GeneID; 4345448; -.
DR Gramene; Os08t0384100-01; Os08t0384100-01; Os08g0384100.
DR KEGG; osa:4345448; -.
DR eggNOG; ENOG502RYBS; Eukaryota.
DR HOGENOM; CLU_069931_0_0_1; -.
DR InParanoid; Q6YW64; -.
DR OMA; REGEYHH; -.
DR OrthoDB; 1222075at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6YW64; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003725; F:double-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0004525; F:ribonuclease III activity; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR GO; GO:0006396; P:RNA processing; IBA:GO_Central.
DR CDD; cd19867; DSRM_DGCR8_rpt1; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR46031:SF37; (WILD MALAYSIAN BANANA) HYPOTHETICAL PROTEIN; 1.
DR PANTHER; PTHR46031; DOUBLE-STRANDED RNA-BINDING PROTEIN 6; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 2.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..312
FT /note="Double-stranded RNA-binding protein 4"
FT /id="PRO_0000404681"
FT DOMAIN 38..107
FT /note="DRBM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT DOMAIN 128..195
FT /note="DRBM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
FT REGION 273..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..312
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 116
FT /note="T -> A (in Ref. 4; AK065829)"
FT /evidence="ECO:0000305"
FT CONFLICT 197
FT /note="N -> D (in Ref. 4; AK065829)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 312 AA; 34198 MW; B262E32B55E98735 CRC64;
MAAATAEPLA VAVAVAHTAT AGTDHSPAPL PPPPPHCNYK SKLQEYLQQA NKQLPIYCTK
CKGEHHQLKF KSTVMVDGEE FSSTFCHRRV KDAEQDAAKV AYDTLLERKE TETDDTDVFE
LIDQDVVFSK SILHEYTTKT KTDQPEYSVT KTEGSVTPYV SSVSFAGHTY TGGAARNKKD
AEQKAARAAV KSLLATNYTS MAKIVRSKEK LIRAISPSGY NKGIDSNPTN KKLPFAPIKF
TPPSIFKLYD GEIDMLSVPQ ALFAPLVAAE EPKVRPAAEP ASNPSEQAVH VSKKHKDNKV
RGPEVKEERV AQ
//
