ID DSE1_CANAL Reviewed; 724 AA.
AC Q59Y20; A0A1D8PI55;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE RecName: Full=Protein DSE1;
DE AltName: Full=Daughter-specific expression protein 1;
GN Name=DSE1; OrderedLocusNames=CAALFM_C208490WA;
GN ORFNames=CaO19.11112, CaO19.3629;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Involved in cell wall metabolism and required for the
CC separation of the mother and daughter cells. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WD repeat DSE1 family. {ECO:0000305}.
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DR EMBL; CP017624; AOW27837.1; -; Genomic_DNA.
DR RefSeq; XP_714471.1; XM_709378.1.
DR AlphaFoldDB; Q59Y20; -.
DR STRING; 237561.Q59Y20; -.
DR EnsemblFungi; C2_08490W_A-T; C2_08490W_A-T-p1; C2_08490W_A.
DR GeneID; 3643899; -.
DR KEGG; cal:CAALFM_C208490WA; -.
DR CGD; CAL0000181989; DSE1.
DR VEuPathDB; FungiDB:C2_08490W_A; -.
DR HOGENOM; CLU_016851_0_0_1; -.
DR InParanoid; Q59Y20; -.
DR OrthoDB; 2020167at2759; -.
DR PHI-base; PHI:3507; -.
DR PRO; PR:Q59Y20; -.
DR Proteomes; UP000000559; Chromosome 2.
DR GO; GO:0009277; C:fungal-type cell wall; ISS:CGD.
DR GO; GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0007155; P:cell adhesion; IMP:CGD.
DR GO; GO:0043709; P:cell adhesion involved in single-species biofilm formation; IMP:CGD.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IMP:CGD.
DR GO; GO:0030447; P:filamentous growth; IMP:CGD.
DR GO; GO:0044182; P:filamentous growth of a population of unicellular organisms; IMP:CGD.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR GO; GO:0044011; P:single-species biofilm formation on inanimate substrate; IMP:CGD.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22850:SF27; CHROMATIN ASSEMBLY FACTOR 1 P55 SUBUNIT; 1.
DR PANTHER; PTHR22850; WD40 REPEAT FAMILY; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell wall biogenesis/degradation;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..724
FT /note="Protein DSE1"
FT /id="PRO_0000285345"
FT REPEAT 98..142
FT /note="WD 1"
FT REPEAT 147..186
FT /note="WD 2"
FT REPEAT 228..266
FT /note="WD 3"
FT REPEAT 334..375
FT /note="WD 4"
FT REPEAT 379..418
FT /note="WD 5"
FT REGION 569..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 81074 MW; D374BBA861420E17 CRC64;
MTDYYEPTFL FRQNAIKRFS PSLSPISSVE SLSLVDSNSI SNNGTTTTTT TTTSSIYQNA
SNSSWLLNPY NVKDTAILNQ SCCLNRTNVK SNYWKIPDES MNLTSMSINK NQGGNPILAI
SSGKSESNLF IYELNLFNNH LIHHHTISLP NIHAMKWINN TRYLVTGNNK GYAHLVSTPK
LATHDVFNTN SNGDFDYNDD DEDDNNSAEI CKRFNHRKHL KQNQLENTIS TPIKHLNFLN
NHENLLSIYN DYLFYWDIKG CHQQTRPSPI SISTVSGIKN FDVPEKNHSS TNTSSANTVA
ICGLFGVSLF DLRDCQFNIP NYNTAQIHDK TQSSYRKLSA NIVKWNPMNT NILAAGHGDG
VIRLWDIRKQ DSYIAELYGH NNYSITTSME WNNNDLFTGS KDGNIIHWDL SNISKDSQWE
ENDNTKLPIS CGLKEGFNSI EFNGKANKLE TKLDQYQCGT ILPASNSSIV AMCSTTTTTS
SNDHDDEEIK ILSIDSSSFL GVHNKVSESI NVNINTNKLY YTEEDIQLLL QSQLNNNNIT
SSSATGSNDT LISFGNNVSQ DSLVKPLTIS RKPTTTIKNN NNNTTTRPTN THTHSASIDE
SIVSVHNVSN DTLVNSPTRF NICESEDEFT FNYVKNNTNN EDQRQSDNRN SSFSSVSSQQ
TQLNNSVESL STVVTDVENE VNHQEHKYMS LLLPVKDTST TTTTTKDNNT NSDQAVTNTP
IISI
//
