ID E0CV46_VITVI Unreviewed; 754 AA.
AC E0CV46;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Dipeptidyl aminopeptidase 4 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_16s0098g01880 {ECO:0000313|EMBL:CBI23007.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI23007.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
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DR EMBL; FN595247; CBI23007.3; -; Genomic_DNA.
DR AlphaFoldDB; E0CV46; -.
DR STRING; 29760.E0CV46; -.
DR ESTHER; vitvi-a5c1g2; DPP4N_Peptidase_S9.
DR PaxDb; 29760-VIT_16s0098g01880-t01; -.
DR EnsemblPlants; Vitvi16g01416_t002; Vitvi16g01416_P002; Vitvi16g01416.
DR Gramene; Vitvi16g01416_t002; Vitvi16g01416_P002; Vitvi16g01416.
DR eggNOG; KOG2281; Eukaryota.
DR HOGENOM; CLU_006105_2_1_1; -.
DR InParanoid; E0CV46; -.
DR OMA; VTHMTPQ; -.
DR Proteomes; UP000009183; Chromosome 16.
DR ExpressionAtlas; E0CV46; baseline and differential.
DR GO; GO:0008239; F:dipeptidyl-peptidase activity; IBA:GO_Central.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF193; DIPEPTIDYL PEPTIDASE 9; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009183}.
FT DOMAIN 146..468
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 555..754
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 754 AA; 85096 MW; E2C82AC05A60EF9E CRC64;
MPVTDTCVAQ SLEDCILFPV EEIVQYPLPG YVAPTSIGFS PDDSLITYLF SPDHTLNRKV
FAFDLETCKQ ELFFSPPDGG LDESNVSPEE KLRRERSRER GLGVTRYEWV KTSLKKRMIM
VPLPVGIYFQ EFSCSKPELK LASTSLSPII DPHLSPDGTM LAYVRDHELH VINLLDDEPR
QLTFGANGNT LTHGLAEYIA QEEMDRKNGY WWSLDSRFIA FTQVDSSEIP LFRIMHQGKS
SVGADAQEDH AYPFAGASNV KVRLGVVSAA GGPATWMDLL CGEMHDGNNE EEYLARVNWM
HGNILTAQVL NRSHSKLKIL KFDINTGQRK VILVEEQDTW VTLHDCFTPL DVGVNRFSGG
FIWASEKTGF RHLYLHDANG TCLGPITEGD WMVEQIAGVN EAAGLVYFTG TLDGPLESNL
YSAKLFLDGN EPLQAPLRLT HGKGKHMVVL DHQMQSFVDI HDSLDFPPRV LLCSLSDGSL
VMPLYEQPFT VPRFKRLQLE PPEIVQIQAN DGTTLFGALY KPDETRFGPP PYKTLISVYG
GPSVQLVCDS WMNTVDMRAQ YLRSRGILVW KLDNRGTARR GLKFESCLKY NAGRIDAEDQ
LTGAEWLIKK GLAKVGHIGL YGWSYGGYLS AMTLARFPDI FRCAVSGAPV TSWDGYDTFY
TEKYMGLPSE NPAGYEYSSV MHHVHKIKGS LLIVHGMIDE NVHFRHTARL VNALVSAGKP
YELLIFPDER HMPRRFRDRI YMEERIWDFI ERNL
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