ID E0DFH1_9CORY Unreviewed; 245 AA.
AC E0DFH1;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=IclR helix-turn-helix domain protein {ECO:0000313|EMBL:EFM49127.1};
GN ORFNames=HMPREF0299_6615 {ECO:0000313|EMBL:EFM49127.1};
OS Corynebacterium matruchotii ATCC 14266.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=553207 {ECO:0000313|EMBL:EFM49127.1, ECO:0000313|Proteomes:UP000004218};
RN [1] {ECO:0000313|EMBL:EFM49127.1, ECO:0000313|Proteomes:UP000004218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14266 {ECO:0000313|EMBL:EFM49127.1,
RC ECO:0000313|Proteomes:UP000004218};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM49127.1}.
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DR EMBL; ACSH02000005; EFM49127.1; -; Genomic_DNA.
DR RefSeq; WP_005526485.1; NZ_ACSH02000005.1.
DR AlphaFoldDB; E0DFH1; -.
DR STRING; 553207.HMPREF0299_6615; -.
DR GeneID; 84574078; -.
DR eggNOG; COG1414; Bacteria.
DR OrthoDB; 3734039at2; -.
DR Proteomes; UP000004218; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF34; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000004218};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..66
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 67..244
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 245 AA; 26012 MW; EB54EBF7C7F3967C CRC64;
MSKVPAATHT LAILRLLMTT DAPISAARIA TQLRLPRSTT YQLLKVMVDA GFVMHLKSHR
TYGLGAAAYS LAQAYSTQQP LVRASTRHAQ ALAKLAGGSA HVSRLSSGME VLYVLEERST
AAVSLITDVG VRLAAERTAS GRAMLAALPD AELKARVDAA GLGRQWQKIH TMVQQVRLRG
WAEETEEVSV GQSSIAAAVL DHTGRPAAAL AVTFTPGVGV DKHAELVAET CRRAQQVHTT
LFGAA
//
