ID   E0E1P5_9FIRM            Unreviewed;       242 AA.
AC   E0E1P5;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Thiamine biosynthesis protein ThiF {ECO:0000313|EMBL:EFM65164.1};
GN   Name=thiF {ECO:0000313|EMBL:EFM65164.1};
GN   ORFNames=HMPREF0634_0182 {ECO:0000313|EMBL:EFM65164.1};
OS   Peptostreptococcus stomatis DSM 17678.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC   Peptostreptococcus.
OX   NCBI_TaxID=596315 {ECO:0000313|EMBL:EFM65164.1, ECO:0000313|Proteomes:UP000003244};
RN   [1] {ECO:0000313|EMBL:EFM65164.1, ECO:0000313|Proteomes:UP000003244}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17678 {ECO:0000313|EMBL:EFM65164.1,
RC   ECO:0000313|Proteomes:UP000003244};
RA   Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA   Nelson K.E.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFM65164.1}.
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DR   EMBL; ADGQ01000019; EFM65164.1; -; Genomic_DNA.
DR   AlphaFoldDB; E0E1P5; -.
DR   STRING; 596315.HMPREF0634_0182; -.
DR   eggNOG; COG0476; Bacteria.
DR   Proteomes; UP000003244; Unassembled WGS sequence.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR012729; ThiF_fam2.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   NCBIfam; TIGR02354; thiF_fam2; 1.
DR   PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   PANTHER; PTHR43267:SF1; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003244}.
FT   DOMAIN          56..239
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   242 AA;  26566 MW;  35814DCB7B5FDE60 CRC64;
     MVKIEGKFEK SREKEENVIS LKRSIYKGLK NINIGGRVLG PQDIFKRNIS DPEGVLARSS
     ICILGLGGLG SNIGVYLARS DIGKLVLVDF DQVEASNLNR QYYSLGHIGM KKTQALVEVI
     RSINPFIDLE VIDTKINRDN IMDIVKGQQI ICEALDDPAT KSMVVSEVLA NSNDKLVIAA
     SGMAGLDDAN LIRTQKKFSR LYLCGDERSD FELTPGMMAP RVSICAGHQA NIILRLIMGL
     EG
//