ID E0NEL3_PEDAC Unreviewed; 894 AA.
AC E0NEL3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Alpha-mannosidase MngB {ECO:0000313|EMBL:EFL96024.1};
DE EC=3.2.1.- {ECO:0000313|EMBL:EFL96024.1};
GN Name=mngB {ECO:0000313|EMBL:EFL96024.1};
GN ORFNames=HMPREF0623_0075 {ECO:0000313|EMBL:EFL96024.1};
OS Pediococcus acidilactici DSM 20284.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus; Pediococcus acidilactici group.
OX NCBI_TaxID=862514 {ECO:0000313|EMBL:EFL96024.1, ECO:0000313|Proteomes:UP000004470};
RN [1] {ECO:0000313|EMBL:EFL96024.1, ECO:0000313|Proteomes:UP000004470}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20284 {ECO:0000313|EMBL:EFL96024.1,
RC ECO:0000313|Proteomes:UP000004470};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFL96024.1}.
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DR EMBL; AEEG01000002; EFL96024.1; -; Genomic_DNA.
DR AlphaFoldDB; E0NEL3; -.
DR CAZy; GH38; Glycoside Hydrolase Family 38.
DR eggNOG; COG0383; Bacteria.
DR HOGENOM; CLU_003442_2_1_9; -.
DR Proteomes; UP000004470; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10815; GH38N_AMII_EcMngB_like; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:EFL96024.1};
KW Hydrolase {ECO:0000313|EMBL:EFL96024.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000004470}.
FT DOMAIN 292..370
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 894 AA; 102965 MW; 080E3B1A6BDC7F47 CRC64;
MEAGKHLSAS FLLKILGLGE RVVMKKIHVI HHTHWDFEWY FTRDEALIQF VYHMDEVFAA
LQAQKVDYYL LDGQMSILDD YLDAYPEKSK EIKKWVNAGR LFIGPWYTQT DELIITGESI
VRNLSLGMKM AQRLGGAQPI GYLPDSFGQG ADMPKIYNGM NIKNAVFWRG LPKEKTANRE
FIWKSEDGSQ VSVANIKNGY FVGVGLIEDD DAKNMMTTVV QGASVDDVPL PVGGDQRYVD
FNLKERISFY NQQLDDAKLV ESNYVKYFQD LKQHQNELDQ VTGEFIDPSV SKIHRSIYSS
RYDQKYLNDK VERRMIYQVE PLMAMAERAG IPYKKALLDK IWKLIVRNHA HDSAGGCNSD
KTNRMILARL VEADQLSYSV VDYLTRKITE SDVNYGENTI TFFNTLPYPI TKRVKFQLSL
KNPAFKLMKD DQKITVDVEK VTKEYHGQIK RDTSAYRDDD FYYKIDCSAR INLPALQWQS
FDVVASEAVP ALLENTTDKS ISDNHFKIEW VDGKLNLTNL NDQTLVEDFM YIEDGGDEGD
TYDYSPAYKN QVYRLDFKDA AVTTRKGRVT SQLILQGTWA VPVDLAARAE NLRNQQINYQ
LELELDGSGR INHELQIHNE AKDHRMRVIN RTNIYAKASY ADTGFGYIER PVVDPHLKDW
QAIGYHEEPT AIFPMIHYVN VHDDERSVSF LTKGIKEYQI TGAQNDRVAL TLFRSVGYLG
RPDLLRRPGV ASGNQFTYIP TPDSQLQKEM HFKWATYISK QFDPAEISKE FMEYAVTNPN
YQAQDLNQFT NTLKYFVMHP LKNTIKAQPF FELVDRRITF SSLTKSIDGT ADLIRVVNLN
KQKVQIDQLI NLDKQYYINE TDFSGRIRKD LGYAASIEKI SFQPGEVKTF KIAR
//
