ID E0NEP8_PEDAC Unreviewed; 395 AA.
AC E0NEP8;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Putative thioredoxin-disulfide reductase {ECO:0000313|EMBL:EFL96059.1};
DE EC=1.8.1.9 {ECO:0000313|EMBL:EFL96059.1};
GN Name=trxB {ECO:0000313|EMBL:EFL96059.1};
GN ORFNames=HMPREF0623_0110 {ECO:0000313|EMBL:EFL96059.1};
OS Pediococcus acidilactici DSM 20284.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus; Pediococcus acidilactici group.
OX NCBI_TaxID=862514 {ECO:0000313|EMBL:EFL96059.1, ECO:0000313|Proteomes:UP000004470};
RN [1] {ECO:0000313|EMBL:EFL96059.1, ECO:0000313|Proteomes:UP000004470}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20284 {ECO:0000313|EMBL:EFL96059.1,
RC ECO:0000313|Proteomes:UP000004470};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFL96059.1}.
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DR EMBL; AEEG01000002; EFL96059.1; -; Genomic_DNA.
DR RefSeq; WP_002831327.1; NZ_GL397067.1.
DR AlphaFoldDB; E0NEP8; -.
DR eggNOG; COG0492; Bacteria.
DR HOGENOM; CLU_031864_5_3_9; -.
DR Proteomes; UP000004470; Unassembled WGS sequence.
DR GO; GO:0004791; F:thioredoxin-disulfide reductase (NADP) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR PANTHER; PTHR48105:SF16; THIOREDOXIN REDUCTASE 1-RELATED; 1.
DR PANTHER; PTHR48105; THIOREDOXIN REDUCTASE 1-RELATED-RELATED; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFL96059.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004470}.
FT DOMAIN 5..295
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 395 AA; 43550 MW; E82BD6F547B29CFA CRC64;
MRKEYDVLIV GGGPGGLTAA IYGGRAELKT LLIEKSGYGG RITETAEVKN YPGVELDSGN
HLMETFKKHA EDAESVELKR TTVTRVQPVE DGFIVSTKRR GDFTAKTVIL DLGTVPRELN
ISGEKEFVGQ GVSYCATCDA EFFKDQEIFV VGAGDQAIEE SEYLAKFAKK INIVVLHDGG
ILDCNEVAAK NIKNNPKVSF IWNSTLAEIK GGEKVEEVVV KNVKTGALTT HTTKGVFFFI
GMTPQTSLVK GLVEMNGHGY IHVNEKQETN LPGLYAIGDC TDNYLKQVIT ACGDGACAVV
AAERYLTEEK QLAQILNDFD AKVAFIFFNP YESQDIDQAT KFENALVEKY KVYRQDVSHQ
TVLFNQLKLN HTVVAALYEH GQLTKIINSI EELEK
//
