ID E0PB03_STREI Unreviewed; 494 AA.
AC E0PB03;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Threonine synthase {ECO:0000313|EMBL:EFM28425.1};
DE EC=4.2.3.1 {ECO:0000313|EMBL:EFM28425.1};
GN Name=thrC {ECO:0000313|EMBL:EFM28425.1};
GN ORFNames=HMPREF9319_0026 {ECO:0000313|EMBL:EFM28425.1};
OS Streptococcus equinus ATCC 700338.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=864569 {ECO:0000313|EMBL:EFM28425.1, ECO:0000313|Proteomes:UP000004290};
RN [1] {ECO:0000313|EMBL:EFM28425.1, ECO:0000313|Proteomes:UP000004290}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700338 {ECO:0000313|EMBL:EFM28425.1,
RC ECO:0000313|Proteomes:UP000004290};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM28425.1}.
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DR EMBL; AEEL01000001; EFM28425.1; -; Genomic_DNA.
DR RefSeq; WP_003062829.1; NZ_GL397128.1.
DR AlphaFoldDB; E0PB03; -.
DR GeneID; 76469486; -.
DR HOGENOM; CLU_015170_3_1_9; -.
DR Proteomes; UP000004290; Unassembled WGS sequence.
DR GO; GO:0004795; F:threonine synthase activity; IEA:UniProtKB-EC.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:EFM28425.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51}.
FT DOMAIN 5..80
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT MOD_RES 112
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 494 AA; 53724 MW; 0C350E7278944248 CRC64;
MTLIYQSTRD ENNKVTASQA ILQGLATDGG LFTPVSLPEV ALDFETLKDA SYQEVAKLVL
SAFLDDFTEE ELAYCIDSAY DAKFDTPEIA PLVKLGDQYN LELFHGSTIA FKDMALSILP
YLLTTSAKKQ GVDNKIVILT ATSGDTGKAA MAGFADVPGT EIIVFYPKDG VSKIQELQMT
TQTGDNTHVV AITGNFDDAQ TDVKRMFNDV DLREKLLAHK TQFSSANSMN VGRLVPQVVY
YVYAYVQLVK AGHIKAGDKV NFTVPTGNFG NILAAYYASQ IGVPVGKLIC ASNENKVLTD
FFTTGTYDKK REFKVTTSPS MDILVSSNLE RLIFHLLGND AAKTKALMEQ LVSEGEYTLP
DVDQSILDLF EAGYATEVET SAEIKRVYEA SDYIEDPHTA VASAVYQKYA ERTGDKTPTV
IASTASPYKF PRVAVEAVSG QAPADDFVAV KELEKLSGVA IPKAVNGLET AEVRHKTVVA
TGDMQKAVEN YLGL
//
