ID E0Q0Y7_9STRE Unreviewed; 371 AA.
AC E0Q0Y7;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Aminotransferase, class V {ECO:0000313|EMBL:EFM35563.1};
DE EC=2.8.1.7 {ECO:0000313|EMBL:EFM35563.1};
GN Name=iscS {ECO:0000313|EMBL:EFM35563.1};
GN ORFNames=HMPREF9189_0718 {ECO:0000313|EMBL:EFM35563.1};
OS Streptococcus sp. oral taxon 071 str. 73H25AP.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=864570 {ECO:0000313|EMBL:EFM35563.1, ECO:0000313|Proteomes:UP000005184};
RN [1] {ECO:0000313|EMBL:EFM35563.1, ECO:0000313|Proteomes:UP000005184}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=73H25AP {ECO:0000313|EMBL:EFM35563.1,
RC ECO:0000313|Proteomes:UP000005184};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU004504};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM35563.1}.
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DR EMBL; AEEP01000008; EFM35563.1; -; Genomic_DNA.
DR RefSeq; WP_000639684.1; NZ_GL397254.1.
DR AlphaFoldDB; E0Q0Y7; -.
DR eggNOG; COG1104; Bacteria.
DR HOGENOM; CLU_003433_0_0_9; -.
DR Proteomes; UP000005184; Unassembled WGS sequence.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:EFM35563.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transferase {ECO:0000313|EMBL:EFM35563.1}.
FT DOMAIN 2..361
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 371 AA; 40640 MW; 5D5D9F07E54384B1 CRC64;
MIYLDNAATT PMSAVAISEM TKVMQETHGN PSSIHSHGRQ AGKLLREARQ ELAQLLGTKS
QHIFFTSGGT ESNNTAIIGY CLRHQNQGKH IITTAIEHHS VLETIDYLVQ HFGFEATIIQ
PVNQEITAQQ IQEALRDDTI LVSTMYANNE TGSLLPIAEI GRVLKEHPAA YHVDAVQAIG
KIPIHPEELG IDFLSASAHK FHGPKGVGFL YASTGDFDSY LHGGDQEQKK RAGTENLAAI
VGMVAALKED LNDQVKHYQK LSALKSTFLE EIAGLDYYLN ESNHQLPYVV NIGFPGQKND
LLLLRLDLEG ISISTGSACT AGVVQTSHVL EAFYGPDSHR LKESVRISLS PLNTEEELKQ
LAQTLKNIIG D
//
