ID E0SA48_ENCIT Unreviewed; 292 AA.
AC E0SA48;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Farnesyl pyrophosphate synthetase {ECO:0000313|EMBL:ADM12670.1};
GN ORFNames=Eint_111710 {ECO:0000313|EMBL:ADM12670.1};
OS Encephalitozoon intestinalis (strain ATCC 50506) (Microsporidian parasite)
OS (Septata intestinalis).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC Encephalitozoon.
OX NCBI_TaxID=876142 {ECO:0000313|EMBL:ADM12670.1, ECO:0000313|Proteomes:UP000002313};
RN [1] {ECO:0000313|EMBL:ADM12670.1, ECO:0000313|Proteomes:UP000002313}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50506 {ECO:0000313|EMBL:ADM12670.1,
RC ECO:0000313|Proteomes:UP000002313};
RX PubMed=20865802; DOI=10.1038/ncomms1082;
RA Corradi N., Pombert J.-F., Farinelli L., Didier E.S., Keeling P.J.;
RT "The complete sequence of the smallest known nuclear genome from the
RT microsporidian Encephalitozoon intestinalis.";
RL Nat. Commun. 1:77-77(2010).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP001952; ADM12670.1; -; Genomic_DNA.
DR RefSeq; XP_003074030.1; XM_003073984.1.
DR AlphaFoldDB; E0SA48; -.
DR GeneID; 9699739; -.
DR KEGG; ein:Eint_111710; -.
DR VEuPathDB; MicrosporidiaDB:Eint_111710; -.
DR HOGENOM; CLU_028376_3_0_1; -.
DR OrthoDB; 509027at2759; -.
DR Proteomes; UP000002313; Chromosome XI.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR039702; FPS1-like.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR PANTHER; PTHR11525:SF0; FARNESYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR11525; FARNESYL-PYROPHOSPHATE SYNTHETASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 292 AA; 34040 MW; 5706635E2F0BF374 CRC64;
MIKEIVKRKV LQLSDYYNKS EILFLLDYNL EGGKELRYKA YIHVLNALNG EMNEKNLTVG
YTIELLQAAL LITDDLMDNS EVRREKPCYY LKRGTKVIKD AFFLLGVIRK MIDKRMKRPY
SYSIFKTCIG QTHDTIRKTR AEYNIEAYTA IAESKTGAYT FYLPAIFGYI SAKKKEPEYL
WDFCNLGALI FQMQDDYLNF FPEKSGKSMN DLEEMKCTWF TSKISQMKNP AVERYFSKGE
VSSDLLSIVK DLFKEYSFTL DKLLARLTFV VDENGKKVLG VFISFLEKRA LV
//
