ID E0SNK8_IGNAA Unreviewed; 494 AA.
AC E0SNK8;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN OrderedLocusNames=Igag_0989 {ECO:0000313|EMBL:ADM27804.1};
OS Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1).
OC Archaea; Thermoproteota; Thermoprotei; Desulfurococcales;
OC Desulfurococcaceae; Ignisphaera.
OX NCBI_TaxID=583356 {ECO:0000313|EMBL:ADM27804.1, ECO:0000313|Proteomes:UP000001304};
RN [1] {ECO:0000313|EMBL:ADM27804.1, ECO:0000313|Proteomes:UP000001304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17230 / JCM 13409 / AQ1.S1
RC {ECO:0000313|Proteomes:UP000001304};
RX PubMed=21304693; DOI=10.4056/sigs.1072907;
RA Goker M., Held B., Lapidus A., Nolan M., Spring S., Yasawong M., Lucas S.,
RA Glavina Del Rio T., Tice H., Cheng J.F., Goodwin L., Tapia R., Pitluck S.,
RA Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Brambilla E., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Detter J.C., Han C., Rohde M., Sikorski J.,
RA Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Ignisphaera aggregans type strain (AQ1.S1).";
RL Stand. Genomic Sci. 3:66-75(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the HerA family.
CC {ECO:0000256|ARBA:ARBA00007816}.
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DR EMBL; CP002098; ADM27804.1; -; Genomic_DNA.
DR AlphaFoldDB; E0SNK8; -.
DR STRING; 583356.Igag_0989; -.
DR KEGG; iag:Igag_0989; -.
DR HOGENOM; CLU_023842_2_0_2; -.
DR BioCyc; IAGG583356:GHAH-972-MONOMER; -.
DR Proteomes; UP000001304; Chromosome.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR018538; HerA_barrel_dom.
DR InterPro; IPR002789; HerA_central.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42957; HELICASE MJ1565-RELATED; 1.
DR PANTHER; PTHR42957:SF1; HELICASE MJ1565-RELATED; 1.
DR Pfam; PF01935; DUF87; 1.
DR Pfam; PF09378; HAS-barrel; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001304}.
FT DOMAIN 21..106
FT /note="Helicase HerA barrel"
FT /evidence="ECO:0000259|Pfam:PF09378"
FT DOMAIN 146..341
FT /note="Helicase HerA central"
FT /evidence="ECO:0000259|Pfam:PF01935"
SQ SEQUENCE 494 AA; 55386 MW; 5992F8D455E2F177 CRC64;
MSLAKQSRGI EASRELQLEL VGYIVGESRP YRAEIVAFRP LMMGEYLYME YYGYRVLAMV
SSSITGSNVI NNNLVDPRDI ERLVKNIRVG EKIYYYRGTI KILGSINGDG DKLYIPPIPP
PPGSEVYKAP KSILSSIFSP EKDMYIRIGT LLREPDVEVR VNINRVVSRH LGILAMTGMG
KSNLVALLAK RIAEIGGTII IFDYHGEYRF LKSRYLNVIK PKLDPWRLDL EEIARLLNIP
RNATRQRMVL HECLESIGNT GNVSFFDGLK RCIQTRIGKY GISAQKVLDA LIAYEGYLKR
FLEEGIGDVI DKIVLGYINV VDLSEIHVHQ ADAIISHWLE RLLEGRKIGV WSNGSKGIPT
PIIVVIEEAH VFIPTDEDSA TKRSASSIAR EGRKFGIGLV VVSQRPRGLD PTILSQLGNL
AILRIVHPED QAYVAKYCEP ITQDLLDELP GLNIGEAILL GEWVSIPTIT KIDLVEEKVS
GFDIDAVSIW RKSF
//
