ID E0V9U3_PEDHC Unreviewed; 559 AA.
AC E0V9U3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Voltage-gated channel, putative {ECO:0000313|EMBL:EEB10149.1, ECO:0000313|EnsemblMetazoa:PHUM020660-PA};
GN Name=8233849 {ECO:0000313|EnsemblMetazoa:PHUM020660-PA};
GN ORFNames=Phum_PHUM020660 {ECO:0000313|EMBL:EEB10149.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB10149.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB10149.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB10149.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB10149.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM020660-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM020660-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AAZO01000248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS234996; EEB10149.1; -; Genomic_DNA.
DR RefSeq; XP_002422887.1; XM_002422842.1.
DR AlphaFoldDB; E0V9U3; -.
DR STRING; 121224.E0V9U3; -.
DR EnsemblMetazoa; PHUM020660-RA; PHUM020660-PA; PHUM020660.
DR GeneID; 8233849; -.
DR KEGG; phu:Phum_PHUM020660; -.
DR CTD; 8233849; -.
DR VEuPathDB; VectorBase:PHUM020660; -.
DR eggNOG; KOG1545; Eukaryota.
DR HOGENOM; CLU_011722_4_0_1; -.
DR InParanoid; E0V9U3; -.
DR OMA; CPSKAAY; -.
DR OrthoDB; 1478695at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF254; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01496; SHAKERCHANEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..145
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 63961 MW; C1BD5A19216CA8DC CRC64;
MSVFNRTTAM SLPKLSSQDE DGPTPHAFTG VVHFEPIPHD HDFCERVVIN VSGLRFETQL
RTLNQFPDTL LGDPARRIRY FDPLRNEYFF DRNRPSFDAI LYYYQSGGRL RRPVNVPLDV
FSEEIKFYEL GELATNKFRE DEGFIKEEEK PLPSHEFQRK VWLLFEYPES SQAARVVAII
SVFVILLSIV IFCLETLPEF KHYNVFNTTT NGTKIEEDEV PEITDPFFLI ETICIIWFTF
ELSVRFLACP NKLNFFRDVM NIIDIIAIIP YFITLATVMA EEEDKLKLPK APVSPQDKST
NQAMSLAILR VIRLVRVFRI FKLSRHSKGL QILGRTLKAS MRELGLLIFF LFIGVILFSS
AVYFAEAGSD QSFFKSIPDA FWWAVVTMTT VGYGDMRPVG VWGKIVGSLC AIAGVLTIAL
PVPVIVSNFN YFYHRETDQE EMQSQNFNHV TSCPYLPGTL GQHLKKSSLS ESSSDMMELD
EDILLTSDVT SKTKLNCNPR HNNNLNGRTK NINKQFYYKE VGGNDGWGEG YGRRAWPWWQ
PARGAKATAA ITSRYSAYS
//
