ID E0VBE1_PEDHC Unreviewed; 520 AA.
AC E0VBE1;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=CXXC-type domain-containing protein {ECO:0000259|PROSITE:PS51058};
GN Name=8239090 {ECO:0000313|EnsemblMetazoa:PHUM058930-PA};
GN ORFNames=Phum_PHUM058930 {ECO:0000313|EMBL:EEB10697.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB10697.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB10697.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB10697.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB10697.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM058930-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM058930-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AAZO01000692; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235028; EEB10697.1; -; Genomic_DNA.
DR RefSeq; XP_002423435.1; XM_002423390.1.
DR AlphaFoldDB; E0VBE1; -.
DR STRING; 121224.E0VBE1; -.
DR EnsemblMetazoa; PHUM058930-RA; PHUM058930-PA; PHUM058930.
DR GeneID; 8239090; -.
DR KEGG; phu:Phum_PHUM058930; -.
DR CTD; 8239090; -.
DR VEuPathDB; VectorBase:PHUM058930; -.
DR eggNOG; ENOG502RYF7; Eukaryota.
DR HOGENOM; CLU_049500_0_0_1; -.
DR InParanoid; E0VBE1; -.
DR OMA; NGYDKKS; -.
DR OrthoDB; 4203385at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR040388; CXXC4/CXXC5.
DR InterPro; IPR002857; Znf_CXXC.
DR PANTHER; PTHR13419:SF0; CXXC-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13419; ZINC FINGER-CONTAINING; 1.
DR Pfam; PF02008; zf-CXXC; 1.
DR PROSITE; PS51058; ZF_CXXC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00509}.
FT DOMAIN 446..486
FT /note="CXXC-type"
FT /evidence="ECO:0000259|PROSITE:PS51058"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..400
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 56043 MW; 3AC2C155F08D6030 CRC64;
MSEGGGSAGP DIGPNYQNSG PTSYSNPPSQ PPTPSSTVQD PPNYQNASEI SENSNETKSN
LNNIHTNSVA SGLPPFSSFA SSDVTEGLGG RLAGDGYLTS DGLTSSTRVM ELSGWDYCYT
DGISGRYLDR DSMPVMIPQP QYRPWESKQD GSGDSIKSTL PSFQSQFGEE LVTTLTTLTP
AACSPAPSVP SPGLPSFHTL SAVNPRYPLV PAPVQAREIP SIQQQFLDER HIHLFQGPPG
QNFTLQPQNG INGQTLTSLN NGTTLTTLNN AQYHPQIINN AQILPSGQIL TPQSHILTPS
SQIITSNGHI ITSSGGQGLT VVSQNSTPTV LTVVKTEPVN IVELKTSSTE PSNLAHHHPN
FQNPMITQGQ QMDSKFGLES PPRGVDGRKK ERRKIRASSL ESSNESDGAL SVESSGQVAA
VSSTAGFKSP MTPGQMNNED TGEKQTKKKR KRCGECIGCQ RKDNCGDCAP CRNDKSHQIC
KMRRCEKLTE KKVGPFILSK TKFFFSGAKI IFYSTKLWIK
//
