ID E0VRT6_PEDHC Unreviewed; 234 AA.
AC E0VRT6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=cAMP-dependent protein kinase type II-alpha regulatory subunit, putative {ECO:0000313|EMBL:EEB16092.1, ECO:0000313|EnsemblMetazoa:PHUM404250-PA};
DE EC=2.7.10.2 {ECO:0000313|EMBL:EEB16092.1};
GN Name=8231091 {ECO:0000313|EnsemblMetazoa:PHUM404250-PA};
GN ORFNames=Phum_PHUM404250 {ECO:0000313|EMBL:EEB16092.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB16092.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16092.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB16092.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16092.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM404250-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM404250-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cAMP-dependent kinase regulatory chain
CC family. {ECO:0000256|ARBA:ARBA00005753}.
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DR EMBL; AAZO01004812; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAZO01004813; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235562; EEB16092.1; -; Genomic_DNA.
DR RefSeq; XP_002428830.1; XM_002428785.1.
DR AlphaFoldDB; E0VRT6; -.
DR STRING; 121224.E0VRT6; -.
DR EnsemblMetazoa; PHUM404250-RA; PHUM404250-PA; PHUM404250.
DR GeneID; 8231091; -.
DR KEGG; phu:Phum_PHUM404250; -.
DR CTD; 8231091; -.
DR VEuPathDB; VectorBase:PHUM404250; -.
DR eggNOG; KOG1113; Eukaryota.
DR HOGENOM; CLU_018310_2_0_1; -.
DR InParanoid; E0VRT6; -.
DR OMA; GDYETQL; -.
DR OrthoDB; 55978at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR11635; CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN; 1.
DR PANTHER; PTHR11635:SF152; CAMP-DEPENDENT PROTEIN KINASE TYPE II REGULATORY SUBUNIT; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR PRINTS; PR00103; CAMPKINASE.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
PE 3: Inferred from homology;
KW cAMP {ECO:0000256|ARBA:ARBA00023149};
KW cAMP-binding {ECO:0000256|ARBA:ARBA00022566};
KW Kinase {ECO:0000313|EMBL:EEB16092.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022566};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transferase {ECO:0000313|EMBL:EEB16092.1}.
FT DOMAIN 57..178
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 193..219
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 234 AA; 27425 MW; 39F80CACCB30CBF5 CRC64;
MRKIKEVVTG KYTDRRKSVF AEAYDPEEDE DDGERIVFPK SDEQRKRLAD SIQNILLFKS
LDKEQMQEIL DAMFERQVQP EEWIIHQGED GDNFYVIERG IFNAYVLREN EAEPMHVHTY
EDFGSFGELA LLYNMPRAAS VKAVTEGSLW AMDRLTFRRI ILKSAFKKRK MYEQLLESVP
MLKALQTLVG VVLDVEAFER LLGPCMQIMK RNINDYEEQL IKIFGSKNNI TDIR
//
