ID E0VTV1_PEDHC Unreviewed; 449 AA.
AC E0VTV1;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=mRNA export factor GLE1 {ECO:0000256|ARBA:ARBA00026227};
DE AltName: Full=GLE1 RNA export mediator {ECO:0000256|ARBA:ARBA00030897};
DE AltName: Full=Nucleoporin GLE1 {ECO:0000256|ARBA:ARBA00029983};
GN Name=8230614 {ECO:0000313|EnsemblMetazoa:PHUM438340-PA};
GN ORFNames=Phum_PHUM438340 {ECO:0000313|EMBL:EEB16807.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB16807.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16807.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB16807.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB16807.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM438340-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM438340-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- FUNCTION: Required for the export of mRNAs containing poly(A) tails
CC from the nucleus into the cytoplasm. May be involved in the terminal
CC step of the mRNA transport through the nuclear pore complex (NPC).
CC {ECO:0000256|ARBA:ARBA00024680}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
CC -!- SIMILARITY: Belongs to the GLE1 family.
CC {ECO:0000256|ARBA:ARBA00011056}.
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DR EMBL; AAZO01005350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235773; EEB16807.1; -; Genomic_DNA.
DR RefSeq; XP_002429545.1; XM_002429500.1.
DR AlphaFoldDB; E0VTV1; -.
DR STRING; 121224.E0VTV1; -.
DR EnsemblMetazoa; PHUM438340-RA; PHUM438340-PA; PHUM438340.
DR GeneID; 8230614; -.
DR KEGG; phu:Phum_PHUM438340; -.
DR CTD; 8230614; -.
DR VEuPathDB; VectorBase:PHUM438340; -.
DR eggNOG; KOG2412; Eukaryota.
DR HOGENOM; CLU_024662_0_0_1; -.
DR InParanoid; E0VTV1; -.
DR OMA; VITELWI; -.
DR OrthoDB; 317142at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.510; GLE1-like; 1.
DR InterPro; IPR012476; GLE1.
DR InterPro; IPR038506; GLE1-like_sf.
DR PANTHER; PTHR12960; GLE-1-RELATED; 1.
DR PANTHER; PTHR12960:SF0; MRNA EXPORT FACTOR GLE1; 1.
DR Pfam; PF07817; GLE1; 1.
PE 3: Inferred from homology;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Receptor {ECO:0000313|EMBL:EEB16807.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 449 AA; 51038 MW; EFCD1B64CA7B24F6 CRC64;
MSGSINGKSY LKKYVVNVSY DSSQNSCQNV LPSILKNKYP KSLYCPAKRK TKKNNTLENE
FNTSGSQHLN TSYSVSNPCR YFKIKRHYKS DDSSDDVNED GDIQTLNIFS PLKKKYKRVR
FSDSNDIISS GYFETFDENK LHSLSDKNFL QKENITTYMD NSLEPLLTDE TMKKFKFNCQ
KAVTIPVNAI SPINASHLTD KYMKLYHLLS GHTVEVGEIK VDASQHPLGI NFCKHLLAKK
FVRQGDLTVS SKPDAAFSIA AVMVSLWVEF PDFGQLVLAQ FHSACPYLAP VFMPQVEGQS
DVDYHKSLGY HYSQNGDVEK QDSFLKRMSG IMRLYAALLI SKPRQPGKMN PLGLSEGWRW
LSALLNLSPR PDICATLLYD FLEVAGNAMF KLYGRQFKKL LAYICQEYFP KLEKVSAGGP
IVRLEGFLQK VLKEEFIPLP NGILPHNFW
//
