ID E0VWZ4_PEDHC Unreviewed; 1022 AA.
AC E0VWZ4;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Ankyrin repeat-containing protein, putative {ECO:0000313|EMBL:EEB17900.1, ECO:0000313|EnsemblMetazoa:PHUM492290-PA};
DE EC=3.1.1.4 {ECO:0000313|EMBL:EEB17900.1};
GN Name=8235876 {ECO:0000313|EnsemblMetazoa:PHUM492290-PA};
GN ORFNames=Phum_PHUM492290 {ECO:0000313|EMBL:EEB17900.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB17900.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17900.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB17900.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB17900.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM492290-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM492290-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AAZO01005954; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235824; EEB17900.1; -; Genomic_DNA.
DR RefSeq; XP_002430638.1; XM_002430593.1.
DR AlphaFoldDB; E0VWZ4; -.
DR STRING; 121224.E0VWZ4; -.
DR EnsemblMetazoa; PHUM492290-RA; PHUM492290-PA; PHUM492290.
DR GeneID; 8235876; -.
DR KEGG; phu:Phum_PHUM492290; -.
DR CTD; 8235876; -.
DR VEuPathDB; VectorBase:PHUM492290; -.
DR eggNOG; KOG0510; Eukaryota.
DR eggNOG; KOG1697; Eukaryota.
DR HOGENOM; CLU_009006_2_0_1; -.
DR InParanoid; E0VWZ4; -.
DR OMA; WQNHVGA; -.
DR OrthoDB; 5476210at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0034703; C:cation channel complex; IEA:UniProt.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR GO; GO:0004623; F:phospholipase A2 activity; IEA:UniProtKB-EC.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR000754; Ribosomal_uS9.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR47143; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR PANTHER; PTHR47143:SF3; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13857; Ank_5; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00380; Ribosomal_S9; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 9.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Hydrolase {ECO:0000313|EMBL:EEB17900.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 532..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 597..615
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..723
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 173..205
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 205..237
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 271..295
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 306..338
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 408..440
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 541..803
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 1022 AA; 115313 MW; 81D3753FA6E33701 CRC64;
MELNFTKDYD QKQPFDRSIS FGRELSVIDT SQKCRTPSFL ERLKSFGEDR ASMLQRSKHI
DLEDSSSSAL DDIIFLDSFE EIHQKGDANV LVSRDVVRQN ILDMMKSGSG NVKLLTDIET
GNTSVNNIEE HFANSSQFEK NVGFLWSVFH RRRDLLDYFL QFNVDVNFSE PQLGFTPLHL
SSFSGCNNCT ALLISKGADV NTLTNKYTPL HCAAFGNAAS TAKLLLKAGA KIVSEKVCNE
TPIHSAVRSK AVDCLQLFIT ENMDLSNMGG CGYSPLHLAA DLGHLQCLQI LLNSNKCDIN
LQTLERKCSA LHLAAENGYY ECLKTLLEYG ADSNAVNYRQ QTPLHAAAKV CSESVELLLK
YGADPNSPDA DNRTPMHAAV CKCESEHSLE ILDYLTMWKG DVNRRDKYGY TPLHIAALNE
LTECVECLIL SGSDVTARTR GGTSALSIIS RKTPAALGAV NQKLDESITT NDPDASKEIV
LMFNFRYLLK NCKRGEVSFL QTLVDEGQKE FLSHPLCEAF LHLKWQKIRK YYITRLIFCL
LFVILLSLYV LTALAYQCYN DSVSDVFPDV EARILIVDPE LCTKKSYFGE LLRRNPIIME
MEWFFLVFIT VLEIFRKIYG FRGYKSFRHY ISQKGNIVEW FVVLSVFLIS FVYTGRTYIW
QNHVGALAVL CGWANLMIMI GNLPIFGSYV AMYTKVQKEF TKLFLAYICL LIGFTVCFCV
IFPKAKQFSN PFVAVIKILV MMTGELEFDS LLENITQEES HSATLLEISA LTTFVFFLLF
VTIILMNLLI GIAVHDIQGL QKTAVLSKLV GQTKLITHIE SALFNGCLPN CFLKLLQITA
LISPSSYRVV VSVKPLNPRE TRLPQDVMRS GLKVAKQKRA KGPTPSARSS MRYPTMKKRK
TMMMMNEEVI ADMRNALSKL MDEVGTIKRL IMAGERNDIL FPLLLTDMLG KVDIECTVEN
GGPSGQAGAL RYAISKTLYT LVDENVRAKM MLAGLTQRDI RRRERKKPGR DGARRRYTWL
KR
//
