ID   E0W3J3_PEDHC            Unreviewed;       741 AA.
AC   E0W3J3;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   24-JAN-2024, entry version 63.
DE   RecName: Full=Tubulin polyglutamylase TTLL2 {ECO:0008006|Google:ProtNLM};
GN   Name=8237078 {ECO:0000313|EnsemblMetazoa:PHUM605220-PA};
GN   ORFNames=Phum_PHUM605220 {ECO:0000313|EMBL:EEB20199.1};
OS   Pediculus humanus subsp. corporis (Body louse).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC   Pediculus.
OX   NCBI_TaxID=121224;
RN   [1] {ECO:0000313|EMBL:EEB20199.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|EMBL:EEB20199.1};
RA   Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA   Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA   Amedeo P., Strausberg R.;
RT   "Annotation of Pediculus humanus corporis strain USDA.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EEB20199.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|EMBL:EEB20199.1};
RG   The Human Body Louse Genome Consortium;
RA   Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT   "The genome of the human body louse.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblMetazoa:PHUM605220-PA}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM605220-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; AAZO01007402; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS235882; EEB20199.1; -; Genomic_DNA.
DR   RefSeq; XP_002432937.1; XM_002432892.1.
DR   AlphaFoldDB; E0W3J3; -.
DR   STRING; 121224.E0W3J3; -.
DR   EnsemblMetazoa; PHUM605220-RA; PHUM605220-PA; PHUM605220.
DR   GeneID; 8237078; -.
DR   KEGG; phu:Phum_PHUM605220; -.
DR   CTD; 8237078; -.
DR   VEuPathDB; VectorBase:PHUM605220; -.
DR   eggNOG; KOG2157; Eukaryota.
DR   HOGENOM; CLU_010131_9_0_1; -.
DR   InParanoid; E0W3J3; -.
DR   OrthoDB; 7265at2759; -.
DR   Proteomes; UP000009046; Unassembled WGS sequence.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR   InterPro; IPR004344; TTL/TTLL_fam.
DR   PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR   PANTHER; PTHR12241:SF118; TUBULIN POLYGLUTAMYLASE TTLL2-RELATED; 1.
DR   Pfam; PF03133; TTL; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR   PROSITE; PS51221; TTL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009046}.
FT   REGION          440..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        451..472
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        473..494
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..516
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        517..531
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   741 AA;  84858 MW;  D3C4E74EFD2007D4 CRC64;
     MSLEEGPFVF RVNENGSGPD LLMQVCAERG WKEYAENNST KDSWNLWWKT SAFSISQHKQ
     LKAWQFTNHM PKGSTICRKD NLARNLKCMK KVYGGIYDIS PPGYNLPLEY TKLVADCSRH
     DDDEDDNQKV WICKPVSQSQ GRGIFLFKSL NDLSYDSNAV VQKYIKNPLL IGGYKFDLRL
     YVCVPSYHPL TVYLYKDGLV RFSTDKFSLS DLNNPFCHLT NSSLNKLGPG YAEQKERIGA
     GCKWSFTQLR QYFQQAGIRD WLLWQRVSAL VTLTILSQST SVPQTINCFE FYGFDVLIDE
     KLKPWLLEVN LSPALGNDCN VDSIVKKPLL HDLFDLLGLP VCYTGLSLFT VYSPPYENEI
     QRYYATHIKS KHEHDAAQRQ MNLTRANYNG HKLTNVSHIR TFGGIKPSSV VLAASAVNKW
     RRKRRSGYLF GPPLRQKYDV DKKRSIKTQS KSDISLRSTN NNVAPASSNK TKLERKTIND
     NDKKLDEKTD EDESSSSSPS PGAGAPNQSQ CKNNTNKTIK RTRDKPDKLK LNGNNDPPVK
     DIKFKSTIKA TCSDNSKIFI EIENLITNDK QGKKKRMEGL PLSKEKRHTK SRIVDFKGPS
     MCEKQKKVLF KNNEHVKKIV LPFNKTIAAS KGFKNRSKNQ PSALWGNGKD WQAPVKREGN
     WERIYPLNNF NNFNQTYEED YLGNKFAIGD KQIKFVVHHI TNFIKYSKQI YYKDIDASEE
     ELNAQLMSHM GMNGNVWLPN K
//