ID E0W3U6_PEDHC Unreviewed; 243 AA.
AC E0W3U6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Chymotrypsin, putative {ECO:0000313|EMBL:EEB20302.1, ECO:0000313|EnsemblMetazoa:PHUM610330-PA};
DE EC=3.4.21.1 {ECO:0000313|EMBL:EEB20302.1};
GN Name=8239697 {ECO:0000313|EnsemblMetazoa:PHUM610330-PA};
GN ORFNames=Phum_PHUM610330 {ECO:0000313|EMBL:EEB20302.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB20302.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB20302.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB20302.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB20302.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM610330-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM610330-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; AAZO01007454; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235883; EEB20302.1; -; Genomic_DNA.
DR RefSeq; XP_002433040.1; XM_002432995.1.
DR AlphaFoldDB; E0W3U6; -.
DR STRING; 121224.E0W3U6; -.
DR EnsemblMetazoa; PHUM610330-RA; PHUM610330-PA; PHUM610330.
DR GeneID; 8239697; -.
DR KEGG; phu:Phum_PHUM610330; -.
DR CTD; 8239697; -.
DR VEuPathDB; VectorBase:PHUM610330; -.
DR eggNOG; KOG3627; Eukaryota.
DR HOGENOM; CLU_006842_7_4_1; -.
DR InParanoid; E0W3U6; -.
DR OrthoDB; 3659930at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24260; -; 1.
DR PANTHER; PTHR24260:SF149; CLIP DOMAIN-CONTAINING SERINE PROTEASE-RELATED; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|RuleBase:RU363034, ECO:0000313|EMBL:EEB20302.1};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Serine protease {ECO:0000256|RuleBase:RU363034}.
FT DOMAIN 15..240
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 243 AA; 26940 MW; 211ACF4707F41258 CRC64;
MKLNDKPQYE TLPLILGGTV APEGSFPFAV SIREKDTDKF FCGGSLIAKQ FVVTAAHCLD
EAHEMMIGVG SVKLSEQKLY KAERIFPYPD YQPPEILHDI ALIKLKKPVE LSPTVQLIDF
PYTKYADEKN VTALGWGQTS TTDPTVPSLL YLEKHTINKT ECERRLSRHK TKIAPGQICL
GSTVNSGMCY GDSGSAMLLE EDGKNYLVGI VSQGIPCAVG YPDIFSRVSY YTDWMNDVMA
KNS
//
