ID E0W4E7_PEDHC Unreviewed; 817 AA.
AC E0W4E7;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Glutamic acid-rich protein, putative {ECO:0000313|EMBL:EEB20503.1};
GN Name=8239902 {ECO:0000313|EnsemblMetazoa:PHUM617710-PA};
GN ORFNames=Phum_PHUM617710 {ECO:0000313|EMBL:EEB20503.1};
OS Pediculus humanus subsp. corporis (Body louse).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Psocodea; Phthiraptera; Anoplura; Pediculidae;
OC Pediculus.
OX NCBI_TaxID=121224;
RN [1] {ECO:0000313|EMBL:EEB20503.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB20503.1};
RA Kirkness E., Hannick L., Hass B., Bruggner R., Lawson D., Bidwell S.,
RA Joardar V., Caler E., Walenz B., Inman J., Schobel S., Galinsky K.,
RA Amedeo P., Strausberg R.;
RT "Annotation of Pediculus humanus corporis strain USDA.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB20503.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=USDA {ECO:0000313|EMBL:EEB20503.1};
RG The Human Body Louse Genome Consortium;
RA Kirkness E., Walenz B., Hass B., Bruggner R., Strausberg R.;
RT "The genome of the human body louse.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:PHUM617710-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:PHUM617710-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AAZO01007556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS235886; EEB20503.1; -; Genomic_DNA.
DR RefSeq; XP_002433241.1; XM_002433196.1.
DR AlphaFoldDB; E0W4E7; -.
DR STRING; 121224.E0W4E7; -.
DR EnsemblMetazoa; PHUM617710-RA; PHUM617710-PA; PHUM617710.
DR GeneID; 8239902; -.
DR KEGG; phu:Phum_PHUM617710; -.
DR CTD; 8239902; -.
DR VEuPathDB; VectorBase:PHUM617710; -.
DR eggNOG; KOG0381; Eukaryota.
DR HOGENOM; CLU_018370_0_0_1; -.
DR InParanoid; E0W4E7; -.
DR OMA; RTAYKEY; -.
DR OrthoDB; 4260911at2759; -.
DR Proteomes; UP000009046; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21999; HMG-box_UBF1_rpt2; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 4.
DR InterPro; IPR029215; HMG_box_5.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR46318; UPSTREAM BINDING TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR46318:SF3; UPSTREAM BINDING TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF14887; HMG_box_5; 1.
DR SMART; SM00398; HMG; 4.
DR SUPFAM; SSF47095; HMG-box; 4.
DR PROSITE; PS50118; HMG_BOX_2; 3.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Reference proteome {ECO:0000313|Proteomes:UP000009046};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 341..409
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 434..502
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 534..601
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 341..409
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 434..502
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 534..601
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 752..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..147
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..638
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..789
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..817
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 817 AA; 94126 MW; 207032C89AEAFA60 CRC64;
MGKKKRDEIN TGKEKSEPEI EKKRAKKEII IKTDNKEKQQ QQQQPPKKQS RSNEKESKKL
TSNKDGTNKN IKSRKYEYTD SSSSSDSESE KNSNKNSNNN KKTVTDSNSD SVDSNTSDSG
DDSSPASEVF KNNKKPNNKK MKVDDDVINK NNTVTNLMIP VKNYDRTTGE KSSSSDSYHS
DTEEEDKKRR KKQKKLLQMQ LNKKTNKKNN NNNFTVASDI KQRDVQSDAD EEGGDNLTSN
NDEVPDWPES DYAELLRRME TQIPPKDNQK FHSRAAKLDW SKIAFGDYDA HECYEVWLAI
SKRVRRFRIL SEILQDAREW VTKPWTNFYR GSKKNRHPDM PPRPLSTYML YYLEQKDKVV
KENPGMEMTQ VSKIISEMYK NLSQEERDKY TDLAAKQRQN FDVKLSEFYR EHPEIAQQQQ
QRKIQGKESS TKGPRKASNP FKLFFQEQLK KHEGGFSAED RKTVEETAKE KWKNMSDEKK
LIWIDWALQD HKRYEDEMRV YRLEHPDYVP PNSSKSILNK DERNIKERLA GKPVKPPNSA
YSLYSRLMLQ SDPDVKSKPP KQRMAEISKM WKKISESQKA LYEKEVRAMQ DSYKLDFASY
LEGLSPEERE IELKKNQPKR KMSGSSGSNN NNNNNSSKVV EEKVKKKEMK NNVTMKNVKS
SSSSSSSNND GGRLILFKDE PLPPPVLSEC STKLNEGERL KEAIKKWNGL SESKKMMYKE
KHKELKDKYI KNYEIFLKSL SKEDLKKFSA LKAQSKHNDN PKGTKESVNG TADDSNEDSD
NDENGSSSDS GSDDSDSDGS GSEKSSKSSS SSDDSNC
//
