ID   E0WJ58_HELPX            Unreviewed;       330 AA.
AC   E0WJ58;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=CagAlpha protein {ECO:0000313|EMBL:CBV36379.1};
GN   Name=cagAlpha {ECO:0000313|EMBL:CBV36379.1};
GN   ORFNames=HP0525 {ECO:0000313|EMBL:CBV36379.1};
OS   Helicobacter pylori (Campylobacter pylori).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=210 {ECO:0000313|EMBL:CBV36379.1};
RN   [1] {ECO:0000313|EMBL:CBV36379.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=LSU2003-1 {ECO:0000313|EMBL:CBV36379.1};
RX   DOI=10.1371/journal.pgen.1001069;
RA   Olbermann P., Josenhans C., Moodley Y., Uhr M., Stamer C., Vauterin M.,
RA   Suerbaum S., Achtman M., Linz B.;
RT   "A global overview of the genetic and functional diversity in the
RT   Helicobacter pylori cag pathogenicity island.";
RL   PLoS Genet. 6:0-0(2010).
CC   -!- SIMILARITY: Belongs to the GSP E family.
CC       {ECO:0000256|ARBA:ARBA00006611}.
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DR   EMBL; FR666843; CBV36379.1; -; Genomic_DNA.
DR   AlphaFoldDB; E0WJ58; -.
DR   GO; GO:0043684; C:type IV secretion system complex; IEA:InterPro.
DR   GO; GO:0044097; P:secretion by the type IV secretion system; IEA:InterPro.
DR   CDD; cd19477; type_II_IV_secretion_ATPases; 1.
DR   Gene3D; 3.30.450.90; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001482; T2SS/T4SS_dom.
DR   InterPro; IPR014155; VirB11.
DR   NCBIfam; TIGR02788; VirB11; 1.
DR   PANTHER; PTHR30486:SF6; CONJUGAL TRANSFER PROTEIN RV3659C-RELATED; 1.
DR   PANTHER; PTHR30486; TWITCHING MOTILITY PROTEIN PILT; 1.
DR   Pfam; PF00437; T2SSE; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          43..290
FT                   /note="Bacterial type II secretion system protein E"
FT                   /evidence="ECO:0000259|Pfam:PF00437"
SQ   SEQUENCE   330 AA;  37520 MW;  097B4582320779E3 CRC64;
     MTEDRLSAED KKFLEVERAL KEAALNPLRH ATEELFGDFL KMENITEICY NGDKVVWVLK
     NNGEWQPFDV RNKKAFSLSR LMHFARCCAS FKKKTIDNYE NPILSSNLAN GERVQIVLSP
     VTVNDETISI SIRIPSKTTY PHSFFEEQGF YNLLDNKEQA ISAIKDGIAI GKNVIVCGGT
     GSGKTTYIKS IMEFIPKEDR IISIEDTEEI VFKHHKNYTQ LFFGGNITSA DCLKSCLRMR
     PDRIILGELR SSEAYDFYNV LCSGHKGTLT TLHAGSSEEA FIRLANMSSS NSAARNIKFE
     SLIEGFKDLI DIIVHINHHK QCDEFYIKHR
//