ID E0WRK4_9ENTR Unreviewed; 434 AA.
AC E0WRK4;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|ARBA:ARBA00016246, ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:EFL92764.1};
GN ORFNames=REG_0608 {ECO:0000313|EMBL:EFL92764.1};
OS Candidatus Regiella insecticola LSR1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Regiella.
OX NCBI_TaxID=663321 {ECO:0000313|EMBL:EFL92764.1, ECO:0000313|Proteomes:UP000005726};
RN [1] {ECO:0000313|EMBL:EFL92764.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSR1 {ECO:0000313|EMBL:EFL92764.1};
RX PubMed=19840097;
RA Degnan P.H., Leonardo T.E., Cass B.N., Hurwitz B., Stern D., Gibbs R.A.,
RA Richards S., Moran N.A.;
RT "Dynamics of genome evolution in facultative symbionts of aphids.";
RL Environ. Microbiol. 0:0-0(2009).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|ARBA:ARBA00025175}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; GL379589; EFL92764.1; -; Genomic_DNA.
DR AlphaFoldDB; E0WRK4; -.
DR STRING; 663321.REG_0608; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_631194_0_0_6; -.
DR Proteomes; UP000005726; Miscellaneous, Scaffold Scaffold1.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:EFL92764.1};
KW Cilium {ECO:0000313|EMBL:EFL92764.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:EFL92764.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005726};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 38..124
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 221..285
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 434 AA; 48627 MW; 08D696F7BA8B5209 CRC64;
MDHFNIVRGI MVDSISGFKI DNPEFKKQAE EMAKNQFYAQ SVSLKNVSLK NERKIFQAEE
NRWGEFQKTL ETFRADLNVL NNADMVQNSV ISSDPQEKYV KISHDSKAIR SSHTVDVLAL
ASEHKIIYKS LDDDQIAKAS GLLTLAINSK SFEIDLSALQ NKTLEGLQQA INTHPDNKGI
VALIYRLDGK KTFSLASSES GVANTMSVTS SLLTGGEERQ AQDAHINIDG QATSNPSNQF
DDIVSGFSIE LKKLTGSSPV SFSLSLDTSA TTQQVEKFVQ AYNALDAAGN DHIINLKRSC
LNEIRELKTR VVQIERSGKL TVDKNLATLL KQNPNALTTI FNGENGLVNR MINKLSVYFD
PPKNIKGKSS ESFIQLNLRR LAEKDKELTA KEKAHQTALE KFKEESEKRL RQNAINELKN
KRFVETHFPS RRNY
//
