ID E0WRN3_9ENTR Unreviewed; 851 AA.
AC E0WRN3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN Name=ftsK {ECO:0000313|EMBL:EFL92793.1};
GN ORFNames=REG_0638 {ECO:0000313|EMBL:EFL92793.1};
OS Candidatus Regiella insecticola LSR1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Regiella.
OX NCBI_TaxID=663321 {ECO:0000313|EMBL:EFL92793.1, ECO:0000313|Proteomes:UP000005726};
RN [1] {ECO:0000313|EMBL:EFL92793.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSR1 {ECO:0000313|EMBL:EFL92793.1};
RX PubMed=19840097;
RA Degnan P.H., Leonardo T.E., Cass B.N., Hurwitz B., Stern D., Gibbs R.A.,
RA Richards S., Moran N.A.;
RT "Dynamics of genome evolution in facultative symbionts of aphids.";
RL Environ. Microbiol. 0:0-0(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; GL379589; EFL92793.1; -; Genomic_DNA.
DR RefSeq; WP_006704491.1; NZ_GL379589.1.
DR AlphaFoldDB; E0WRN3; -.
DR STRING; 663321.REG_0638; -.
DR eggNOG; COG1674; Bacteria.
DR HOGENOM; CLU_001981_7_1_6; -.
DR Proteomes; UP000005726; Miscellaneous, Scaffold Scaffold1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:EFL92793.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000005726};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 498..711
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 515..522
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 851 AA; 93928 MW; 7A229EF58697868E CRC64;
MNQEYIQNNT MPAKKPTVRR RFFLKAWLIM MVLFAGYLMV SLISFNPSDP SWSQTAWHEP
IHNLGGGVGA WLADMLFFIF GIVAYVIPLL GVTFCQIVLR HKKKSNEPFD YFFISLRLIG
SLALVLSACS LAALSIDDLY YFPSGGVIGS LFGNLMLLNF NSTAGTVCLL FIWGAGLTLF
TGWSWLLIAE KIVWVVLNGL HFICDYRHKK GYRHQSAELA VSPTAISPTA IEQTTITDDD
RLFSLSSSAK NEISSEIKEI NEVKEVKEEE PSACFLDEPP LTSETSLTDE ANKAKLPSIE
FFTAPKENIE NAPVAQSDEA TLSSDNTKMA DEAVASVPET LPDTLIHPFL MRNDSPLVKP
TTPLPTFDLL SSPSSEKPQV DREALKQTAL LVETRLADYR VKAKVVGISP GPVITRFDLD
LAPGVKAARI SSLSRDLARS LSAIAVRVVE VIPGKPYVGL ELPNPYRQTV YLREVLDCPV
FRETRSPLAM VLGKDIAGQP VVADLAQMPH LLVAGTTGSG KSVGVNAMIL SILYKATPDE
VRFIMIDPKM LELSVYEGIP HLLTQVVTDM KDAANALRWC VAEMERRYKL MSALGVRNLA
NYNERVLQAE NMGRPIPDPF WKPKESMGLS PPMLEKLPYI VVMVDEFADL MMTVGKKVEE
LIAQLAQKAR AAGIHLVLAT QRPSVDVITG LIKANIPTRI AFTVSSKIDS RTILDQAVAE
SLLGMGDMLY MAPNSSIPIR IHGAFVRDQE VHAVVNDWKA RGRPQYIENI LSESEENEGG
NSAGGEETLD PLFDQAVNFV LEKRRASISA VQRQFRIGYN RAARIIEQME AQQIVSAPNH
SGNREVLAPE G
//
