ID E0YQ46_9CAUD Unreviewed; 163 AA.
AC E0YQ46;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE SubName: Full=HNH endonuclease {ECO:0000313|EMBL:ADL71228.1};
GN Name=46 {ECO:0000313|EMBL:ADL71228.1};
GN ORFNames=ISLAND3_46 {ECO:0000313|EMBL:ADL71228.1};
OS Mycobacterium phage Island3.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Chebruvirinae; Brujitavirus; Brujitavirus brujita.
OX NCBI_TaxID=861048 {ECO:0000313|EMBL:ADL71228.1, ECO:0000313|Proteomes:UP000000526};
RN [1] {ECO:0000313|EMBL:ADL71228.1, ECO:0000313|Proteomes:UP000000526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21298013; DOI=10.1371/journal.pone.0016329;
RA Pope W.H., Jacobs-Sera D., Russell D.A., Peebles C.L., Al-Atrache Z.,
RA Alcoser T.A., Alexander L.M., Alfano M.B., Alford S.T., Amy N.E.,
RA Anderson M.D., Anderson A.G., Ang A.A., Ares M.Jr., Barber A.J.,
RA Barker L.P., Barrett J.M., Barshop W.D., Bauerle C.M., Bayles I.M.,
RA Belfield K.L., Best A.A., Borjon A.Jr., Bowman C.A., Boyer C.A.,
RA Bradley K.W., Bradley V.A., Broadway L.N., Budwal K., Busby K.N.,
RA Campbell I.W., Campbell A.M., Carey A., Caruso S.M., Chew R.D.,
RA Cockburn C.L., Cohen L.B., Corajod J.M., Cresawn S.G., Davis K.R., Deng L.,
RA Denver D.R., Dixon B.R., Ekram S., Elgin S.C., Engelsen A.E., English B.E.,
RA Erb M.L., Estrada C., Filliger L.Z., Findley A.M., Forbes L., Forsyth M.H.,
RA Fox T.M., Fritz M.J., Garcia R., George Z.D., Georges A.E.,
RA Gissendanner C.R., Goff S., Goldstein R., Gordon K.C., Green R.D.,
RA Guerra S.L., Guiney-Olsen K.R., Guiza B.G., Haghighat L., Hagopian G.V.,
RA Harmon C.J., Harmson J.S., Hartzog G.A., Harvey S.E., He S., He K.J.,
RA Healy K.E., Higinbotham E.R., Hildebrandt E.N., Ho J.H., Hogan G.M.,
RA Hohenstein V.G., Holz N.A., Huang V.J., Hufford E.L., Hynes P.M.,
RA Jackson A.S., Jansen E.C., Jarvik J., Jasinto P.G., Jordan T.C., Kasza T.,
RA Katelyn M.A., Kelsey J.S., Kerrigan L.A., Khaw D., Kim J., Knutter J.Z.,
RA Ko C.C., Larkin G.V., Laroche J.R., Latif A., Leuba K.D., Leuba S.I.,
RA Lewis L.O., Loesser-Casey K.E., Long C.A., Lopez A.J., Lowery N., Lu T.Q.,
RA Mac V., Masters I.R., McCloud J.J., McDonough M.J., Medenbach A.J.,
RA Menon A., Miller R., Morgan B.K., Ng P.C., Nguyen E., Nguyen K.T.,
RA Nguyen E.T., Nicholson K.M., Parnell L.A., Peirce C.E., Perz A.M.,
RA Peterson L.J., Pferdehirt R.E., Philip S.V., Pogliano K., Pogliano J.,
RA Polley T., Puopolo E.J., Rabinowitz H.S., Resiss M.J., Rhyan C.N.,
RA Robinson Y.M., Rodriguez L.L., Rose A.C., Rubin J.D., Ruby J.A., Saha M.S.,
RA Sandoz J.W., Savitskaya J., Schipper D.J., Schnitzler C.E., Schott A.R.,
RA Segal J.B., Shaffer C.D., Sheldon K.E., Shepard E.M., Shepardson J.W.,
RA Shroff M.K., Simmons J.M., Simms E.F., Simpson B.M., Sinclair K.M.,
RA Sjoholm R.L., Slette I.J., Spaulding B.C., Straub C.L., Stukey J.,
RA Sughrue T., Tang T.Y., Tatyana L.M., Taylor S.B., Taylor B.J., Temple L.M.,
RA Thompson J.V., Tokarz M.P., Trapani S.E., Troum A.P., Tsay J., Tubbs A.T.,
RA Walton J.M., Wang D.H., Wang H., Warner J.R., Weisser E.G., Wendler S.C.,
RA Weston-Hafer K.A., Whelan H.M., Williamson K.E., Willis A.N.,
RA Wirtshafter H.S., Wong T.W., Wu P., Yang Y., Yee B.C., Zaidins D.A.,
RA Zhang B., Zuniga M.Y., Hendrix R.W., Hatfull G.F.;
RT "Expanding the diversity of mycobacteriophages: insights into genome
RT architecture and evolution.";
RL PLoS ONE 6:E16329-E16329(2011).
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DR EMBL; HM152765; ADL71228.1; -; Genomic_DNA.
DR Proteomes; UP000000526; Genome.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.75.20; -; 1.
DR InterPro; IPR044925; His-Me_finger_sf.
DR InterPro; IPR003615; HNH_nuc.
DR InterPro; IPR010902; NUMOD4.
DR Pfam; PF13392; HNH_3; 1.
DR Pfam; PF07463; NUMOD4; 1.
DR SUPFAM; SSF54060; His-Me finger endonucleases; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:ADL71228.1};
KW Hydrolase {ECO:0000313|EMBL:ADL71228.1};
KW Nuclease {ECO:0000313|EMBL:ADL71228.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000526}.
FT DOMAIN 4..59
FT /note="NUMOD4"
FT /evidence="ECO:0000259|Pfam:PF07463"
FT DOMAIN 70..113
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|Pfam:PF13392"
SQ SEQUENCE 163 AA; 18950 MW; B8FC259C0670CAE8 CRC64;
MTYEKWLPVV GYEGRYEVSN QGRVRSVGRI VKIGENNRRI FGRILKRSRG SRYLYVGLSD
DDGRVKRMNV HILVLTAFVG PCPEGMEALH GPGGSHDNSL ANLRWDTRDE NNRDLVRHSR
HHYSRRTRCD KGHELKPRKR YGRESRYCPT CQRDAARQRK ASA
//
