ID E0ZCL3_PICSI Unreviewed; 227 AA.
AC E0ZCL3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Auxin efflux carrier-like protein {ECO:0000313|EMBL:ADM76088.1};
DE Flags: Fragment;
OS Picea sitchensis (Sitka spruce) (Pinus sitchensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Pinopsida; Pinidae; Conifers I; Pinales; Pinaceae; Picea.
OX NCBI_TaxID=3332 {ECO:0000313|EMBL:ADM76088.1};
RN [1] {ECO:0000313|EMBL:ADM76088.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CR301 {ECO:0000313|EMBL:ADM76088.1};
RX PubMed=20738783; DOI=10.1111/j.1365-294X.2010.04767.x;
RA Holliday J.A., Yuen M., Ritland K., Aitken S.N.;
RT "Postglacial history of a widespread conifer produces inverse clines in
RT selective neutrality tests.";
RL Mol. Ecol. 19:3857-3864(2010).
CC -!- FUNCTION: Involved in cellular auxin homeostasis by regulating auxin
CC metabolism. Regulates intracellular auxin accumulation at the
CC endoplasmic reticulum and thus auxin availability for nuclear auxin
CC signaling. {ECO:0000256|ARBA:ARBA00025100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
CC {ECO:0000256|ARBA:ARBA00025752}.
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DR EMBL; HM200404; ADM76088.1; -; mRNA.
DR AlphaFoldDB; E0ZCL3; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0080162; P:endoplasmic reticulum to cytosol auxin transport; IEA:InterPro.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR045033; PILS1/3/4/5/7.
DR PANTHER; PTHR31651:SF33; OS09G0491740 PROTEIN; 1.
DR PANTHER; PTHR31651; TRANSPORTER; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 2: Evidence at transcript level;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADM76088.1"
FT NON_TER 227
FT /evidence="ECO:0000313|EMBL:ADM76088.1"
SQ SEQUENCE 227 AA; 24238 MW; 9956DC2EC30CBEDF CRC64;
EEKIPNIDYA GETSKLLQTI QIIPEVPSSG GDYPSDKQSA SGLVVVNSSS SKKPSCFQAW
PRKVKQYMKK TADLLFEELK APPTIGVIAG FMVGAIPPVK ALIVGASAPL RVIQDSISLL
GDGAIPGIIL LMGGHLVKGL SSSKLRPMII VLIICAKFVL LPVIGIFVVK GASNLGLLPA
DPLYHFVLMI QYTVPPAMNI GTMAQLFNVG EQECSVIFFW TYLLAAS
//
