ID E1BH63_BOVIN Unreviewed; 315 AA.
AC E1BH63;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN Name=OR1AF3 {ECO:0000313|Ensembl:ENSBTAP00000050957.3,
GN ECO:0000313|VGNC:VGNC:100547};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000050957.3, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000050957.3, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000050957.3,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000050957.3}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000050957.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Putative odorant or sperm cell receptor.
CC {ECO:0000256|ARBA:ARBA00003929}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR AlphaFoldDB; E1BH63; -.
DR SMR; E1BH63; -.
DR STRING; 9913.ENSBTAP00000050957; -.
DR PaxDb; 9913-ENSBTAP00000050957; -.
DR Ensembl; ENSBTAT00000056786.3; ENSBTAP00000050957.3; ENSBTAG00000038665.3.
DR VEuPathDB; HostDB:ENSBTAG00000038665; -.
DR VGNC; VGNC:100547; OR1AF3.
DR eggNOG; ENOG502QVH7; Eukaryota.
DR GeneTree; ENSGT00940000165831; -.
DR HOGENOM; CLU_012526_1_3_1; -.
DR InParanoid; E1BH63; -.
DR OMA; MPRGNQS; -.
DR TreeFam; TF337210; -.
DR Proteomes; UP000009136; Chromosome 11.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR CDD; cd15235; 7tmA_OR1A-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR48001; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR48001:SF129; OLFACTORY RECEPTOR; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363047};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW Olfaction {ECO:0000256|RuleBase:RU363047};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 27..50
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 100..122
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 143..164
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 205..223
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 275..294
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT DOMAIN 43..292
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 315 AA; 35707 MW; AB61243BC37979DB CRC64;
TAMTRGNQSH ITEFLLLGLS SDPKQQVWLF ASFLVMYLVN VGGNSVIIAA IQGDVRLHTP
MYFFLSNLSF VDICFTNVIV PRMLANMQSK SKKVPFTQCL MQMYFFVACA ITDSFLLAAM
ALDRYVAICH PLRYTTTMNP RCCLQLVTVS WLVSHLHSLT HTILMARLSF CGPNIIHHFF
CDVQPLLMLS CSDTSLNELL AFTEGSFVIM SPFIFITVSY VYITRAVLRV PSGRGRYKVF
STCGSHLTVV ALYYGTAISV YIHPSSTYSV TKDRVVTVIY TVVIPMLNPF IYSLRNRDMK
QALRKLARRK EQNKH
//
