ID E1BLC3_BOVIN Unreviewed; 1698 AA.
AC E1BLC3;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Ankyrin repeat domain containing 26 {ECO:0000313|Ensembl:ENSBTAP00000022622.6};
GN Name=ANKRD26 {ECO:0000313|Ensembl:ENSBTAP00000022622.6};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000022622.6, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000022622.6, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000022622.6,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000022622.6}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000022622.6};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR SMR; E1BLC3; -.
DR STRING; 9913.ENSBTAP00000022622; -.
DR PaxDb; 9913-ENSBTAP00000022622; -.
DR Ensembl; ENSBTAT00000022622.6; ENSBTAP00000022622.6; ENSBTAG00000008288.6.
DR VEuPathDB; HostDB:ENSBTAG00000008288; -.
DR eggNOG; ENOG502QR0R; Eukaryota.
DR GeneTree; ENSGT00940000153661; -.
DR HOGENOM; CLU_001111_0_0_1; -.
DR InParanoid; E1BLC3; -.
DR OMA; QCQMKEV; -.
DR TreeFam; TF333496; -.
DR Reactome; R-BTA-9696264; RND3 GTPase cycle.
DR Reactome; R-BTA-9696270; RND2 GTPase cycle.
DR Reactome; R-BTA-9696273; RND1 GTPase cycle.
DR Proteomes; UP000009136; Chromosome 13.
DR Bgee; ENSBTAG00000008288; Expressed in semen and 111 other cell types or tissues.
DR ExpressionAtlas; E1BLC3; baseline.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR039497; CC144C-like_CC_dom.
DR InterPro; IPR021885; DUF3496.
DR PANTHER; PTHR24147; ANKYRIN REPEAT DOMAIN 36-RELATED; 1.
DR PANTHER; PTHR24147:SF60; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 26-RELATED; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF14915; CCDC144C; 1.
DR Pfam; PF12001; DUF3496; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 4.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT REPEAT 75..107
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 108..140
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 141..173
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 174..206
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 898..1201
FT /note="CCDC144C-like coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF14915"
FT DOMAIN 1507..1614
FT /note="DUF3496"
FT /evidence="ECO:0000259|Pfam:PF12001"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 730..855
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 891..925
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 962..1003
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1029..1448
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1507..1537
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 216..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..519
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..555
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..609
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..668
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1698 AA; 193882 MW; 2D5E34C95C04C110 CRC64;
MKKIFGFGSK KGESPLGSSI SPGRDGGHRI NLQPGYRIRD KDLGKIHKAA IVGNVAKVQQ
ILLLGKNGLN DRDKMNRTAL HLACANGHSA VVTLLLERKC LLNLCDNENR TALMKAVECQ
EEECATLLLE HGADPNVMDV SGNTALHYAV FCQNISLAAK LLSYDANIEA RNKDDLTPLS
LAVSERKQQM VEFLAKKEAN IHAVDKMQSI RQLISEYKEE RPKTPPENSN PEDESSEEDS
LSRFSNKPGV DSWPTSDDED LDLETKNVLK PSLTKLMNAS QQSRRNIEAK CGIVRPESTT
FSEDNNSDSE IEDVVETIPE PSPGVQGFSH PAFPSAEPLP QPLKSLAGLG LTKEGATKPE
IVDKESDTDI IERAPQEQIN HDHLSSVDAT HKNNRSDMMS ALGLGEEEDI ESPWDSESIS
ESLPQKYVDL LSGAAGQRGK NTLNGQVEDV SYIPSCMIGS RNFKMAKLEE PRHVGIPVAH
MDSPEKYPNV KPAVLVKDSV PSKTVGMKDL QTSSSAELDL EMTSEEEEEK PVGDKNNHSQ
VEEEKKKHKS SEVEISDNVC DTADESGLIQ QRKSGGNSSQ EFAAMENEGS DSDPDVHRKE
VKKKDNSKWT PEGCVTAPIF EKTDSLTGGL LHVNDDSILS EVDQDDDRPA KKTSNENNKV
KEQINSVDDL DDLTQSSETA SEDGELLYYK NSMLLIEQLD TGCKDSVSLL KIRDTILSYE
RLVELKKSHC ELLKGKIKKM ESKVRGLQKE LSETKEVKSQ LEHQKVEWER ELGSLRFTLK
QEEEQRRNAD MLYEKIREQL RRKEDQYSKE VEMKQQLELT LRALEMELKT VRNDLNQVIE
ERNDTQKQLS RERNARILQD EILANHLAKQ KEIEMANKEM NSEVSDSCEE AKDLLHKNHM
LQEEIAMLRL EMDAVKIQNQ EKEKKYFEDI EIVKGKNDDL QKAIKVNEET LTKTVSHYTG
QLNALTAENT MLNSKLENEK ESKQRLETEV ESYRSRLAAA SHDHDQCQTS KRDLELAFQR
ARDEWLHLQD KMKSDAANLK DNNEMLSQQL SRAESKFNNL EIKLHHTRDS LREKILMLER
VQRDLSQTEC QKQEIEHMYQ NEQGKVNKYI GKQESLEERL SQLQSENMLL RQQLDDAQNK
ADSKEKTVIS IQDQFQQIVR KLHAESEKQG LMLEERNKEL VKECDHLKER MYQYENEKAE
REAGVRQLQQ ELADTLKKQS MSEASLEVLS RYRANLEVEA QDLKKKLGQL TSQLQEAQDQ
LTEAVRCAEK TQDRVQKLEI ENAELQTTVK KQAGKIEQLQ KNLLSTRSSE DEKEQLKKYI
ELKQSLENSL DQEKKKNSEL EKEITGFKKL LKMTRRKLNE YENGELSFHG DLKTSQTEMD
IQINKLKHKI EDLTAELEAA SSKCLHLDAK NQVLREELLS MKGMQKKCEK LEEKKKKLEQ
EVVHLRSHIE MNMIEHSQVE QYKREIEERA RQDLVEKLKE VNLFLQIQAA SQENLEQLQE
KNNASIRSQM ELRIKDLESE LSKVKTLQED SHKAELEKYK QLYLVELEVR KSLEGKLDKT
HERLAVISTK LEVEKEQNRS LLSTLSTRPV LEPPCVGNFN NPVVLNGNLT PRANVGFSTS
IPRPSNNSME TYLTKMRQEL DRSITRELRE AAAEFESESY GLSPLGATDG SNLSEDLLLK
TSQEYVQILK KKYDLKDK
//
