ID E1EYY1_GIAIA Unreviewed; 645 AA.
AC E1EYY1;
DT 30-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Kinase, NEK {ECO:0000313|EMBL:EFO64614.1};
GN ORFNames=GLP15_2993 {ECO:0000313|EMBL:EFO64614.1};
OS Giardia intestinalis (strain P15) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=658858 {ECO:0000313|EMBL:EFO64614.1, ECO:0000313|Proteomes:UP000008974};
RN [1] {ECO:0000313|EMBL:EFO64614.1, ECO:0000313|Proteomes:UP000008974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P15 {ECO:0000313|EMBL:EFO64614.1,
RC ECO:0000313|Proteomes:UP000008974};
RX PubMed=20929575; DOI=10.1186/1471-2164-11-543;
RA Jerlstrom-Hultqvist J., Franzen O., Ankarklev J., Xu F., Nohynkova E.,
RA Andersson J.O., Svard S.G., Andersson B.;
RT "Genome analysis and comparative genomics of a Giardia intestinalis
RT assemblage E isolate.";
RL BMC Genomics 11:543-543(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFO64614.1}.
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DR EMBL; ACVC01000076; EFO64614.1; -; Genomic_DNA.
DR AlphaFoldDB; E1EYY1; -.
DR EnsemblProtists; EFO64614; EFO64614; GLP15_2993.
DR VEuPathDB; GiardiaDB:GLP15_2993; -.
DR OMA; WCPLLYA; -.
DR OrthoDB; 51836at2759; -.
DR Proteomes; UP000008974; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00180; PKc; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EFO64614.1};
KW Transferase {ECO:0000313|EMBL:EFO64614.1}.
FT DOMAIN 9..252
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 645 AA; 70975 MW; 48602896A11397A4 CRC64;
MRDAWAHLYN DMHTVSQKRR WTSYYAYRAD STRKVILKRI DLSNLETRGS NTLAWAYSQL
KGLSNSYVVR CSVAHYTPGD SLLLESSFEE GCNLIDYIRH NCASCEPVSE ETLWPILFQI
SVGLAYLHTP AGKGVILHRN LTPANVLVVA NGAVKISDIW LGPLFSDDEP IMFRAPELQS
SSNFSAKADV YSMGRIIAEF CTRGPSSVKA ITRSVLESHG YTSAFATLLL ACLDPDSGKR
PMAWNVAEQS AVIRELRATK FYAHITASSS EETQIELPSM FTDSKTSLML AAERGSLVGV
QTLLYEAGVV WSGPRELPGT EVITATATSL SLLNGHKDCF KLLAKLEVGL AGVTPLMLYA
TGIVDLPSNP ITLEATVAAY CGATCMGITA LMIASMCNIP ALFSLLRKEL LLLDSYGRSA
LVYLRDAEKD TCAALLHIAD EDGAQVHPLS KELILDEELN TELVSTSDDL WGQDHFGWCP
LLYAISFNCV CGMRCILSHT KEPPPNSILE TALHIVLASQ NSDEVLSELV AYLDKYRITL
RARRRYGDVT LIKTELMHAA AKGNKTEVRK YIHQLGKNVA NLEGGTALIC AASGGHVECC
QLLYRELGMK DRHGRTALDH AKEGGHSDCM WVLRHEFSLL KNESQ
//
